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Evaluation of Left Atrial Function by Real-time 3-D Echocardiography in Patients with Systemic Lupus Erythematosus (SLE). Real-time 3-D echocardiography may have better diagnostic value than traditional echo indexes in detecting subclinical cardiac dysfunction in patients with SLE. PubMed, J Rheumatol, 12/15/2014. (Also see: Symptoms and Complications of Lupus)

Borderline pulmonary arterial pressure (BoPAP) in systemic sclerosis patients: a post-hoc analysis of the DETECT study. In this exploratory post–hoc analysis of the DETECT study population patients with BoPAP could be distinguished from patients with normal mean pulmonary artery pressures and pulmonary arterial hypertension. PubMed, Arthritis Res Ther, 2014 Dec 10;16(6):493. (Also see: Pulmonary Hypertension)

No longer just a smoker's disease, lung cancer gets treatments. Lung cancer lags behind other forms of cancer in research and awareness, largely because many people feel it's self-inflicted: 80 percent get the disease from smoking. Chicago Tribune, 12/14/2014. (Also see: Lung Cancer)

Chronic leg ulcers in adult patients with rheumatological diseases — a 7-year retrospective review. Management of chronic leg ulcers in rheumatological patients is challenging and careful clinicopathological correlation and treatment of the underlying cause is important. PubMed, Int Wound J, 2014 Dec;11(6):601-4. (Also see: Leg and Foot Ulcers)

Role of Cellular Senescence and NOX4-Mediated Oxidative Stress in Systemic Sclerosis (SSc) Pathogenesis. Numerous studies have implicated oxidative stress in SSc pathogenesis, suggesting a plausible mechanism in which excessive oxidative stress induces cellular senescence and that the molecular events play an important role in the fibrotic and fibroproliferative vasculopathy characteristic of SSc. PubMed, Curr Rheumatol Rep, 2015 Jan;17(1):473. (Also see: Causes of Scleroderma: Fibroblasts)

How and why to drink less at the holidays. Holidays are a time when alcohol intake can get away from you. You can, however, cut down and still be of good cheer. Chicago Tribune, 12/16/2014.

Increased risk of ischaemic stroke among patients with multiple sclerosis. Multiple sclerosis is declared to be associated with an increased risk in developing stroke, which requires closer attention to this group of patients for stroke prevention, especially in the younger population. PubMed, Eur J Neurol, 11/29/2014. (Also see: Symptoms of Multiple Sclerosis)

Systemic sclerosis (SSc) induces pronounced peripheral vascular dysfunction characterized by blunted peripheral vasoreactivity and endothelial dysfunction. Compared to healthy controls, SSc patients had significantly smaller brachial artery diameter and blunted peripheral vascular reactivity and endothelial function. PubMed, Clin Rheumatol, 12/16/2014. (Also see: Vascular Involvement in Systemic Scleroderma)

Implant that eases agony of arthritis by zapping a nerve. A tiny disc planted under the skin could offer a revolutionary rheumatoid arthritis treatment and reduce crippling joint pain. Mail Online, 12/22/2014. (Also see: Treatments for Rheumatoid Arthritis)

Association Between Psoriasis and Asthma: A Population-Based Retrospective Cohort Analysis. Our study results indicate that patients with psoriasis are associated with increased risk of asthma development. PubMed, Br J Dermatol, 11/10/2014. (Also see: Psoriasis and Psoriatic Arthritis)

Prognosis in Scleroderma: Sex and the Joints. Joint synovitis and tendon friction rubs are factors which predict disease progression in patients with early systemic sclerosis. The disease is more severe in men and there is a higher risk of severe cardiovascular involvement in men. MedPage Today, 10/29/2014. (Also see: Prognosis and Mortality)

Significant retinopathy risk with long-term hydroxychloroquine. Long-term use of hydroxychloroquine may carry a significant risk of toxic retinopathy. Healthy Living, 10/16/2014. (Also see: Antimalarials)

Etiopathogenic Role of Surfactant Protein D (SP-D) in the Clinical and Immunological Expression of Primary Sjögren Syndrome (pSS). High SP-D levels were found with severe glandular involvement, hypergammaglobulinemia, leukopenia, extraglandular manifestations, and positive anti-Ro/La antibodies. PubMed, J Rheumatol, 2014 Nov 1. (Also see: Sjogren's Research: Antibodies)

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