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Assessment of visual and auditory evoked potentials (VEP) in multiple sclerosis (MS) patients with and without fatigue. Significant, usually asymmetrical VEP and brainstem auditory evoked potentials (BAEP) abnormalities were found in fatigued MS patients, with no relationships to disease-related variables. EP may be considered an electrophysiological marker of fatigue in MS patients. PubMed, Neurol Sci, 2014 Sep 21. (Also see:MS Research)

Low-dose pulse cyclophosphamide (CYC) in interstitial lung disease associated with systemic sclerosis (SSc-ILD): Efficacy of maintenance immunosuppression. The study supports the use of low-dose pulse CYC as induction therapy of recently deteriorated SSc-ILD. Moreover, it suggests that azathioprine should be administered to CYC-responsive patients but does not show any definite effect of micophenolic acid in unresponsive patients. ScienceDirect, 09/08/2014. (Also see: Immunosuppressants)

Breakthrough Replicates Human Brain Cells for Use in Alzheimer's Research. For the first time, and to the astonishment of many of their colleagues, researchers created what they call Alzheimer's in a Dish — a petri dish with human brain cells that develop the telltale structures of Alzheimer's disease. New York Times, 10/12/2014.

Vitamin D status in rheumatoid arthritis (RA) patients: relation to clinical manifestations, disease activity, quality of life (QoL) and fibromyalgia syndrome (FMS). Special attention is required regarding vitamin D levels in RA patients with FMS and decreased QoL. Vitamin D should be corrected and supplementation considered among the RA management armamentarium. PubMed, Int J Rheum Dis, 2014 Oct 7. (Also see: Rheumatoid Arthritis Treatments, Fibromyalgia and Vitamin D Deficiency)

Assessment of myocardial fibrosis and microvascular damage in systemic sclerosis (SSc) by magnetic resonance imaging (MRI) and coronary angiotomography. The prevalence of myocardial fibrosis on MRI attributable to SSc is 45%, is more frequent and severe in diffuse scleroderma, is associated with lower left ventricular ejection fraction and affects mainly basal left ventricular walls. PubMed, Rheumatology (Oxford), 2014 Sep 18. (Also see:Diagnosis of Scleroderma Heart Involvement)

Can Celiac Disease Affect the Brain? The prevalence of celiac disease is indeed rising and symptoms are increasingly understood to manifest beyond the gut, including occasionally in the brain. Gluten sensitivity may yet prove to be real and measurable. New York Times, 10/11/2014. (Also see: Celiac Disease and Gluten Sensitivity)

Identification of Previously Undiagnosed Diabetes and Prediabetes in the Inpatient Setting Using Risk Factor and Hemoglobin A1C Screening. The presence of certain risk factors such as age and hypertension may be an indication for diabetes screening. PubMed, Ann Pharmacother, 2014 Nov;48(11):1434-9. (Also see: Diagnosis of Diabetes)

Screening of human papillomavirus (HPV) infection in women with systemic sclerosis (SSc). This study is the first to evaluate HPV status in women with systemic sclerosis (SSc) and researchers found that HR HPV52 was the most common genotype with a greater multi-HPV infection rate. PubMed, Clin Exp Rheumatol. 2014 Aug 15. (Also see: Causes of Scleroderma: Infection)

Curiosity may kill the cat, but here's why it's good for your memory. A new study in the journal "Neuron" reveals that when we pursue what piques our curiosity we better remember it — and, in the process, retain other knowledge. Today Health, 10/02/2014.

Association of history of surgery for endometriosis with severity of deeply infiltrating endometriosis. A history of surgery for endometriosis correlates with the presence and severity of deeply infiltrating endometriosis, so a thorough preoperative assessment is necessary before undertaking subsequent surgeries. PubMed, Obstet Gynecol, 2014 Oct;124(4):709-17. (Also see: Endometriosis)

Validation of a Novel Radiographic Scoring System for Calcinosis Affecting the Hands of Patients with Systemic Sclerosis (SSc). We developed a novel radiographic scoring system that is feasible with excellent reliability, which accounts for the area coverage, density, and anatomic location of calcinosis affecting the hands in patients with SSc. PubMed, Arthritis Care Res. 2014 Aug 22. (Also see: Calcinosis)

Chiropractic care may ease back-related leg pain. People with leg pain related to back problems had more short-term relief if they received chiropractic care along with exercise and advice, rather than exercise and advice alone, a new study has found. Chicago Tribune, 09/15/2014.

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