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MEDICAL NEWS

Predictors for health improvement in patients with fibromyalgia (FM): a 2-year follow-up study. Recently diagnosed FM patients who report fewer physical limitations may experience more improvement in health if they are at work and have a positive attitude towards participating in an offered health-care intervention. PubMed, Clin Rheumatol, 2015 Jan;34(1):133-41. (Also see: Treatments for Fibromyalgia)

Rituximab in diffuse cutaneous systemic sclerosis (SSc): should we be using it today? We summarize the therapeutic use of rituximab in SSc and the basic science evidence suggesting that B cells and autoantibodies are the primary drivers of fibrosis in skin and lung tissue. PubMed, Rheumatology (Oxford), 07/01/2015. (Also see: Causes of Scleroderma: B Cells and T Cells and Scleroderma Clinical Trials)

How Vitamin D May Fight Colon Cancer. Higher levels of vitamin D have been associated with a reduced risk of colon cancer in many observational studies. New York Times, 01/15/2015. (Also see: Vitamin D Deficiency and Cancer)

High fidelity between saliva proteomics and the salivary glands' biological state defines biomarker-signatures for primary Sjögren's syndrome (SS). The SS-related molecular landscape conveyed by saliva showed great congruence with histopathology features evoked by SS and advances understanding of this disease at a molecular level. PubMed, Arthritis Rheumatol, 12/29/2014. (Also see: Diagnosis of Sjogren's Syndrome)

Three cases of bullous morphea: histopathologic findings with implications regarding pathogenesis. All of our cases showed hemorrhagic content in the bullae, which suggests local trauma as a mechanism involved in bulla formation. PubMed, J Cutan Pathol, 11/04/2014. (Also see:Rare Types of Morphea)

Blueberries May Lower Blood Pressure. Can a cup of blueberries keep the doctor away? Maybe. New York Times, 01/14/2015. (Also see: Food Guide for Autoimmune Disease and Illnesses)

The Overlap and Distinction of Self-Reported Symptoms between Interstitial Cystitis/Bladder Pain Syndrome and Overactive Bladder: A Questionnaire Based Analysis. There is considerable overlap of self-reported symptoms between interstitial cystitis/bladder pain syndrome and overactive bladder. PubMed, J Urol. 2014 Dec;192(6):1679-86. (Also see: Interstitial Cystitis)

Undifferentiated Connective Tissue Disease at risk for Systemic Sclerosis (SSc) (so far referred to as very early/early SSc or pre-SSc). This nosographic approach is instrumental to plan future studies devoted to investigate validated biomarkers heralding the development of major vascular disease manifestations as well as skin and/or organ fibrosis in patients at risk. PubMed, Autoimmun Rev, 11/18/2014. (Also see: Undifferentiated Connective Tissue Disease)

Beyond bed spins: Now we know why boozy snoozing is bad for slumber. While experts have known for years that pre-slumber alcohol causes poor sleep, researchers finally reveal why: drinking interrupts our brain waves as we doze. Today Health, 01/16/2015. (Also see: Sleep Disorders)

Coffee or tea consumption and the risk of rheumatoid arthritis (RA): a meta-analysis. High coffee consumption is associated with an elevated risk of RA development. The association between coffee and RA was found in seropositive RA, but not in seronegative RA. PubMed, Clin Rheumatol, 2014 Nov;33(11):1575-83. (Also see: Causes of Rheumatoid Arthritis)

Myofibroblasts in cutaneous fibrosis originate from adiponectin-positive intradermal progenitors. There is a novel link between intradermal adipose loss and dermal fibrosis, and we demonstrate that adiponectin–positive intradermal progenitors give rise to dermal myofibroblasts. PubMed, Arthritis Rheumatol, 12/10/2014. (Also see: Skin Fibrosis)

Breaking the pain barrier. Chronic pain is suffered by up to 10 million Britons – for many, it's worse in winter. So what's the best way to tackle it? The Telegraph, 01/17/2015. (Also see: Pain Management)

Blood Test Could Prevent Medication Trial and Error for Rheumatoid Arthritis Patients. A molecule in the blood shows promise as a marker to predict whether individual rheumatoid arthritis patients are likely to benefit from biologic medications or other drugs should be tried. PubMed, Mayo Clinic News Network, 11/17/2014. (Also see:Treatments for Rheumatoid Arthritis)

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