Running for SCLERO.ORG: Sponsor Earl Manns in Green Bay Marathon, May 18, 2008! I'm running in honor of my daughter Mya, and in memory of Sherrill Knaggs. Posted 05-07-08. (Also see Donate Now, Earl Manns, and Sherrill Knaggs)

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Hi All

I'm curious, yet again.

I believe our disease is active when things begin to happen, like showing up in our bloodwork, T-spots, etc, etc. But am I wrong, is this disease considered active only when it is full blown?

Also, does the pattern change when it's full blown (ie, from centromere to speckled or is speckled a different autoimmune disease all together)?

Thanks.