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Why are women predisposed to autoimmune rheumatic diseases? In searching for an explanation for this female excess, most attention has focused on hormonal changes - both exogenous changes (for example, oral contraceptive pill) and fluctuations in endogenous hormone levels particularly related to menstruation and pregnancy history. J.E. Oliver. Arthritis Research & Therapy. October 26 2009, 11:252. (Also see: Causes of Autoimmunity)

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