Cellular and molecular aspects of vascular dysfunction in systemic sclerosis. Despite progress in treating the symptoms of vascular disease in SSc, the underlying mechanisms remain poorly understood. An improved knowledge of the molecular and cellular pathways that contribute to SSc vasculopathy could help in the design of effective therapies in the future. Trojanowska M. (PubMed) Nat Rev Rheumatol. 2010 Jun 29. (Also see: Vascular Involvement)
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Cellular and molecular aspects of vascular dysfunction in systemic sclerosis
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