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Gene expression profiling in circulating endothelial cells from systemic sclerosis patients shows an altered control of apoptosis and angiogenesis tha


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#1 Jeannie McClelland

Jeannie McClelland

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Posted 09 August 2010 - 11:16 AM

Gene expression profiling in circulating endothelial cells from systemic sclerosis patients shows an altered control of apoptosis and angiogenesis that is modified by Iloprost infusion. We report here that circulating endothelial cells in patients with Systemic Sclerosis show an altered expression of genes involved in the control of apoptosis and angiogenesis. Moreover we describe that Iloprost infusion has a strong effect on endothelial cells and progenitors since it is able to modulate both their number and their gene expression profile. Elisa Tinazzi. Arthritis Research & Therapy 2010, 12:R131. (Also see: Endothelial cells and Scleroderma Treatments)

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Jeannie McClelland
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