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A 3-factor epistatic model predicts digital ulcers (DU) in Italian scleroderma patients


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#1 Jeannie McClelland

Jeannie McClelland

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Posted 31 August 2010 - 10:42 AM

A 3-factor epistatic model predicts digital ulcers (DU) in Italian scleroderma patients. Biological interpretation via Petri net showed that IL-6 is a key factor in determining digital ulcers (DUs) occurrence and that this cytokines may synergise with HLA-B*3501 to determine DUs onset. Lorenzo Beretta. European Journal of Internal Medicine Volume 21, Issue 4, Pages 347-353 (August 2010). (Also see: Digital Ulcers)

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Jeannie McClelland
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International Scleroderma Network