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Combination of RXs

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#1 lcdavison



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Posted 09 December 2010 - 04:57 AM

Haven't been on here for a while, but things seems to be going well. I hope most of you all can say the same. I posted early in October that my 13 (now 14) year old son was diagnosed with scleroderma. He's doing really well. We had an echo-cardiogram done in November which came out excellent (whew!). My question to throw out is regarding his meds. Our doctor seemed to think my son was handling his meds well, as all his blood tests showed, so he upped his dosage of methotrexate to 1cc weekly, added Plaquenil, and we're still on Prednisone. We'll stop Prednisone at the end of this month, though. So, has anyone else used this combo? I've done some research and this seems to be a common approach to rheumatoid arthritis, but I saw no mention of scleroderma.

Any thoughts? Thanks!

#2 Amanda Thorpe

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Posted 09 December 2010 - 05:26 AM

Hello Lcdavidson

Methotrexate and plaquenil are both used for rheumatic diseases such as scleroderma. There are others on the forum taking the combo who will hopefully join in with their experiences.

I'm only on methotrexate myself and have been for some time, I think it's helpful,

Take care and keep posting.
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#3 Jeannie McClelland

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Posted 09 December 2010 - 08:18 AM

Hi lcdavidson,

I just wanted to congratulate you and your son on how well he is doing. That's wonderful news. I hope this next year (and those following) continue to bring good results.

All the best,
Jeannie McClelland
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#4 janey


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Posted 13 December 2010 - 03:17 PM

Hey LC,

Glad to read that your son's ECG came out well. Have you checked out the information we have methotrexate and plaquenil? The methotrexate section has a study about methotrexate in juvenile scleroderma. You might find it interesting. Combination therapies are sometimes used with scleroderma and other rheumatic diseases so apparently your son's doctor feels that such a treatment is needed at this time.

You mentioned that your son will be stopping the prednisone at the end of this month. Is he already in the tapering process? If not, please talk to his doctor, because usually, one has to slowly come off of prednisone to prevent withdrawal side effects.

I hope that he continues to show improvement!
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#5 Margaret


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Posted 14 December 2010 - 01:13 AM

Hi LC ,

I'm am happy to hear your son is doing well. :emoticons-yes: My son started with symptoms of sine Sclero/UCTD at age 18 and was put on Plaquenil. He's doing quite well now, 4 years later, with only the Plaquenil and Prilosec combo. He needs the Prilosec because he still has some esophageal dysmotility. He had such a horrible reaction to Prednisone (for pneumonia) that I doubt I would ever put him on that drug again.

Take care, Everyone.