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The multiple faces of autoimmune-mediated bone loss


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#1 CraigR

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Posted 30 December 2010 - 05:08 PM

The multiple faces of autoimmune-mediated bone loss. This review discusses current understanding of the mechanisms of autoimmune-mediated bone loss in view of new insight from two new fields of research: osteoimmunology, which analyzes the direct effect of immune cells on bone. Schett G. Nat Rev Endocrinol. 2010 Nov 2. (Also see: Osteoporosis)

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#2 debonair susie

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Posted 31 December 2010 - 07:09 AM

Craig,
I, for one, read this (abstract) with great interest. I believe there are MANY of us (ladies) who struggle with this particular problem.

It truly doesn't seem to make much difference how much vitamin D I take, along with calcium, I am really having trouble being able to elevate my levels! :crying:

Are there any others out there who have a success story to share (with me)?! Help!!! I really am struggling!
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#3 CraigR

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Posted 02 January 2011 - 03:34 PM

Susie,

It's not just the ladies! I have osteoporosis, largely due to low testosterone level following chemo for cancer. It seems the autoimmune process may contribute to this. Like you, no amount of vitamin D or calcium was sufficient for it, and I take alendronate.

Craig

#4 Joelf

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Posted 02 January 2011 - 08:01 PM

Hi Susie

This was interesting to me too, as I have osteopenia in my hips. It was discovered at The Royal Brompton Hospital when they gave me a bone density scan, as I was going to be taking steroids for a long time. Like Craig, I take Alendronic acid and a calcium and vitamin D supplement which The Brompton recommended.

My mother has very bad osteoporosis and also takes Alendronic acid; since being on the tablets I haven't actually been in a position where I might break any bones (thankfully!) but I do notice that my nails have improved so hopefully it's working and strengthening my bone density. At the very least I've acquired fabulous long nails so that's got to be a bonus!! :emoticons-yes: ;)

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#5 debonair susie

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Posted 08 January 2011 - 10:11 AM

Thanks, Craig.

I realize that you fellas can also suffer from this awful deficiency. Not that misery loves company in My case, but it is comforting to know there is something I might try and that may be the Alendronic Acid that both you and Jo take.

However, though my finger nails are disappearing, I'm glad there is good news for others, in that department!
Special Hugs,

Susie Kraft
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International Scleroderma Network (ISN)