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Involvement of functional autoantibodies against vascular receptors in systemic sclerosis (SSc)


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#1 Jeannie McClelland

Jeannie McClelland

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Posted 04 February 2011 - 04:49 PM

Involvement of functional autoantibodies against vascular receptors in systemic sclerosis (SSc). Functional autoimmunity directed at angiotensin II type 1 receptor (AT1R) and endothelin-1 type A receptor (ETAR) is common in patients with SSc. AT1R and ETAR autoantibodies could contribute to disease pathogenesis and may serve as biomarkers for risk assessment of disease progression. Gabriela Riemekasten, Annals of Rheumatic Diseases, 15 November 2010. (Also see: Autoantibodies)

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