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Notch signalling regulates fibroblast activation and collagen release in systemic sclerosis (SSc)


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#1 janey

janey

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Posted 02 June 2011 - 06:16 AM

Notch signalling regulates fibroblast activation and collagen release in systemic sclerosis (SSc).

It was shown that Notch signalling is activated in SSc and plays an important role in fibroblast activation and collagen release. Inhibition of Notch signalling might be an effective strategy to selectively prevent the aberrant activation of SSc fibroblasts. Clara Dees, Ann. rheumatologist.Dis. 30 March 2011 (Also see: Fibroblasts)

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