Jump to content


Biomarker for Diffuse Scleroderma skin has been discovered!


Photo

Any advice about blood tests?


  • Please log in to reply
3 replies to this topic

#1 Perseverance

Perseverance

    Newbie

  • Members
  • Pip
  • 1 posts

Posted 17 April 2012 - 06:38 AM

Hi, I'm a 23 year old male who is currently Active Duty Military (for six years now). I have been having wrist/hand pain for around 7 months now (pretty chronic, though it has gotten better) and initially I thought it was due to overuse/misuse as I used to lift very heavy weights six days a week.


Anyway, fast forward to today when I got my labwork. My doctor said I tested positive for the Centromere antibody. Couple that with my wrist pain and I guess you guys know why I am here. Some of it the doctor briefly explained to me.


I am very concerned about this, so I would highly appreciate any information about this.

Thanks

#2 Amanda Thorpe

Amanda Thorpe

    Platinum Plus Member

  • ISN Senior Support Specialist
  • PipPipPipPipPipPipPipPipPipPipPip
  • 2,927 posts
  • Location:U.K.

Posted 19 April 2012 - 02:24 PM

Hello Perseverance

Welcome to the forums. May I recommend some of our videos about diagnosis of scleroderma and symptoms of scleroderma and of course difficult diagnosis of scleroderma.

A diagnosis of scleroderma is best made from clinical symptoms, medical history and physical examination, blood tests help to categorise and further diagnose scleroderma but as you can see they should not be used as the basis for a diagnosis nor used to rule one out. I have scleroderma but my blood tests have always indicated I don't so in my case they are a red herring and I am not the only one. In addition there have been many people with blood work positive for scleroderma but they never have any symptoms.

If you are concerned about a diagnosis of scleroderma your best bet is to get in with a scleroderma expert.

Take care.
Amanda Thorpe
ISN Sclero Forums Senior Support Specialist
ISN Video Presentations Manager
ISN Blogger

(Retired) ISN Sclero Forums Assistant Manager

(Retired) ISN Email Support Specialist
International Scleroderma Network (ISN)

#3 judyt

judyt

    Gold Member

  • ISN Support Specialists
  • PipPipPipPipPipPip
  • 640 posts
  • Location:Auckland, New Zealand

Posted 19 April 2012 - 03:40 PM

In contrast to Amanda's experience, I have had clinical symptoms of one sort or another - mainly internal organs - since I was about 12 years of age. All those years of asking what was wrong came to nothing until 2003 when I was 59 and had an emergency admission to hospital vomiting blood!! At last somebody did some detailed blood tests and came up with ANA with centromere pattern. A diagnosis of CREST followed, because I had all those obvious symptoms.

You don't say if you have any other clinical signs other than painful wrists and in spite of the scary stories you have no doubt read you may get away without anything else happening.

Some of us draw the short straw and have a really hard time of it as we get older and others sail through almost oblivious. I personally seem to have got the medium straw!! and have times of relative calm followed by some stormy bits.

It is easy to get scared out of your wits, as I did for a while, but it is best to just wait and see. There is not much you can do to change things but being aware and speaking up when you notice things happening is the best you can do. If there is a Scleroderma Expert you can consult I would suggest you do that. I have never been in the same country as an expert so haven't had the opportunity although I think it would have helped in the early days.

Good luck and best wishes

JudyT

#4 Joelf

Joelf

    Star Ruby Member

  • ISN Root Admin
  • PipPipPipPipPipPipPipPipPipPipPipPipPip
  • 4,610 posts
  • Location:West Sussex

Posted 20 April 2012 - 12:45 AM

Hi Perseverence,

I'm afraid I can't add anything to the excellent advice you've received so far from Amanda and Judy so I'll just say welcome to these forums and do let us know how you're faring!

Kind regards,

Jo Frowde
ISN Assistant Webmaster

SD World Webmaster
ISN Sclero Forums Manager
ISN News Manager

ISN Hotline Support Specialist
ISN Chat Host
International Scleroderma Network (ISN)