Vitamin D Supplementation: What's Known, What to Do, and What's Needed. In patients with documented vitamin D deficiency, a cumulative dose of at least 600,000 IU administered over several weeks appears to be necessary to replenish vitamin D stores. Single large doses of 300,000-500,000 IU should be avoided. Pharmacotherapy. 2012 Apr;32(4):354-82. (Also see: Vitamin D Deficiency)
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Vitamin D Supplementation: What's Known, What to Do, and What's Needed
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