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Augmented Inducible costimulator (ICOS) expression in patients with early diffuse cutaneous systemic sclerosis (dcSsc).

diffuse scleroderma

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#1 Joelf

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Posted 23 March 2013 - 12:05 AM

Augmented Inducible costimulator (ICOS) expression in patients with early diffuse cutaneous systemic sclerosis (dcSsc).

 

Augmented ICOS signalling may contribute to the pathogenesis of Systemic Sclerosis (SSc) during early progressive disease. Soluble ICOS levels may be used as a serum marker for the activity and severity of SSc. Pub Med Rheumatology (Oxford). 2013 Feb;52(2):242-51. (Also see: Overview of B Cells and T Cells)

 

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