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Estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis (Ssc).


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#1 Joelf

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Posted 27 March 2013 - 06:00 AM

Estradiol promotes the development of a fibrotic phenotype and is increased in the serum of patients with systemic sclerosis (Ssc).

 

Our findings implicate estrogens in the fibrotic process and may explain the preponderance of SSc in women. Pub Med Arthritis Res Ther. 2013 Jan 10;15(1):R10. (Also see: Causes of Scleroderma: Hormones and Chromosones)

 

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