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Key roles for interferon- and TGF-beta-regulated genes, and macrophage activation in progressive lung fibrosis associated with Systemic Sclerosis.

pulmonary fibrosis

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#1 Joelf

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Posted 13 February 2014 - 12:33 PM

Key roles for interferon- and TGF-beta-regulated genes, and macrophage activation in progressive lung fibrosis associated with Systemic Sclerosis.

 

This highlights major pathogenic pathways relevant to progressive pulmonary fibrosis in SSc-ILD: macrophage activation, and upregulation of TGF-beta- and IFN-regulated genes. PubMed, Arthritis Rheum, 2013 Nov 27. (Also see: Pulmonary Fibrosis)

 

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