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Biomarker for Diffuse Scleroderma skin has been discovered!


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Lipoic acid (LA) plays a role in scleroderma: insights obtained from scleroderma (SSc) dermal fibroblasts.

lipoic acid skin fibrosis

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#1 Joelf

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Posted 25 October 2014 - 03:56 AM

Lipoic acid (LA) plays a role in scleroderma: insights obtained from scleroderma (SSc) dermal fibroblasts.

 

Dihydrolipoic acid (DHLA) not only acts as an antioxidant but also an antifibrotic since it has the ability to reverse the profibrotic phenotype of SSc dermal fibroblasts. Also thiol antioxidants, including N-acetylcysteine and LA/DHLA, could be beneficial for patients with SSc. PubMed, Arthritis Res Ther. 2014 Aug 15;16(5):411. (Also see: Lipoic Acid and Skin Fibrosis Research)

 

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