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The human leukocyte antigen (HLA) profiles of mixed connective tissue disease (MCTD) differ distinctly from the profiles of clinically related connective tissue diseases.

MCTD

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#1 Joelf

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Posted 13 November 2014 - 11:58 AM

The human leukocyte antigen (HLA) profiles of mixed connective tissue disease (MCTD) differ distinctly from the profiles of clinically related connective tissue diseases.

 

Novel HLA alleles associated with MCTD and disease subsets were identified and DRB1*04:01 was confirmed as a major risk allele. Altogether, the data reinforce the notion of MCTD as a disease entity distinct from lupus, scleroderma and polymyositis. PubMed, Rheumatology, 2014 Sep 3. (Also see: Mixed Connective Tissue Disease)

 

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