I'm new here, and new to all things systemic sclerosis. I've been seeing doctors and had all sorts of tests done to find a reason for my symptoms, which include lower back pain and muscle tightness in my legs. I was referred to a rheumatologist by my GP, to see if something rheumatism-related could be going on. I don't really have any such symptoms though, so no joint stiffness or pain etc.
All my bloodwork has come back negative, except for the test for RNA polymerase III. My rheumatologist is actually a bit baffled why the lab did this specific test, as she most recently only ordered a test battery concerning muscles. There has been no mention of systemic sclerosis before and no indications towards it. If I try really hard, I might think of a few symptoms that I might have, for instance my nail capillaries in a couple of fingers have always been a bit weird, and in the past year I've developed a slightly rough spot in the skin on each foot. This spot is exactly in the place that touches the floor when I sit on the floor cross-legged (which I've been doing a lot lately with my toddler), so I just put it down to constant pressure on that spot. Maybe it's something more...? I also have very cold feet, but they never turn white so no Raynaud's I guess, and bad circulation runs in my family.
I'm a bit lost at the moment as my rheumatologist was so surprised by the test result that she didn't really give me any information. I have another appointment with her next week, and she will discuss with the lab before that so hopefully I'll get information then. I've been googling (of course...) and it seems RNA polymerase III is highly specific to the diffuse form of SSc so I'm quite worried. I guess I'm looking for reassurance that my positive result might be false or that it doesn't necessarily lead to diffuse SSc!
Any advice would be appreciated :)