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Safety and effectiveness of mycophenolate in systemic sclerosis. A systematic review.


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#1 Joelf


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Posted 13 July 2015 - 08:13 AM

Safety and effectiveness of mycophenolate in systemic sclerosis. A systematic review.


Mycophenolate-associated gastrointestinal adverse events are common in SSc, but not severe enough to preclude its use and it may be effective in improving or stabilizing interstitial lung disease and skin involvement. PubMed, PLoS One, 2015 May 1;10(5):e0124205. (Also see Immunosuppressants)


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#2 miocean


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Posted 13 July 2015 - 02:43 PM

I have been on myfortic or mycophenolate acid since my kidney transplant in 2010. I had almost immediate improvements in skin score and my lungs were stable until 2013. Since then there has been an increase in fibrosis including honeycombing and I have needed to use oxygen. Although all tests are stable since 2013 I have increased shortness of breath, even with the oxygen. I have suffered with horrible diarrhea since my transplant and right now my dose is reduced until I recover from this latest bout which landed me in the hospital with dehydration and acute renal failure. The dose will be increased as I am able to tolerate it as it is known to help stabilize lung disease.



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