UEDVT could be the first clinical symptom of Antiphospholipid syndrome, and may be the first clinical manifestation of preceding the development of Systemic Lupus Erythematosus by several years. PubMed, Cent Eur J Immunol, 2015;40(3):307–310. (Also see Antiphospholipid Syndrome and Antibodies in Lupus)
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