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Trigger


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#1 Joe

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Posted 06 June 2007 - 07:58 PM

Two weeks before my first symptoms of Scleroderma, I tried Lunesta as a sleep aid for insomnia. I seemed to have a reaction to Lunesta. I remember waking up and all my muscles were rigid and my wrists were bent and my chin was pushed hard into my chest. It was not normal and quite shocking. I stopped right away but right after that my first symptoms appeared and progressed to eventual Kidney failure and Systemic Scleroderma.

I feel that Lunesta was the trigger for my disease. This is obviously a personal observation and can't be proved one way or the other. I have read that there are known triggers for Scleroderma. I was wondering if anyone else tried Lunesta or Ambien prior to first symptoms of if you think something else was a trigger?

Joe

#2 jlf

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Posted 09 June 2007 - 01:47 AM

Dear Joe,

I have not heard of Lunesta causing scleroderma but isn't it well documented about silica and other substances? so, who knows? Maybe for you this was the trigger. For me, and I know it without doubt it was being septic after surgery in 1988. I had a FANA in 12 of 1988 which was negative (during sepsis) - in February 1989 had my first positive FANA. So, I firmly believe in scleroderma being 'triggered'. Boy has it been a ride since.

Wishing you well.
JLF

#3 Sam

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Posted 09 June 2007 - 02:18 AM

Joe I have no idea if anything triggered me haivng scleroderma. I was real young when I didn't feel good and was tired all the time as I am now. I had my children at a young age. And when I was 21 I had found out I had raynauds then diagnosis with sclero in 1996. So who knows.
Sam

#4 RememberingToSmile

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Posted 09 June 2007 - 03:29 AM

I've always had a sensitivity to certain drugs and most antibiotics [hives and rashes]. The year before, I had a Lyme infection that I let disseminate before seeking treatment, as well as one of the eczema viruses. Then there were a couple colds I had picked up at the office immediately before the first symptoms appeared when I took many cold meds and ibuprofen.

I spent a lot of time trying to figure out what I did to cause my illness. I am content now with the idea that there was a combination of factors that became the spark or trigger... mostly it's just chance and the way I was programmed.

Later I read that this is a typical stage for most traumatic events - whether chronic illness, cancer, accident, attack, etc.

It may be different for the type of sclero... I have diffuse

Take care,
RTS

#5 TJ903

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Posted 09 June 2007 - 04:37 AM

Joe,

My husband and I both swear that it was too much Kenelog (steroid injections) that I received for my neck and back pain. I had injections every week for a month and a half. After the total body swelling went down a year later (2006) I still had a patch of skin on my left forearm that refused to go back to normal. It spread from there. I was treated for water retention for 6-8 months and finally sent to a rheumatologist and was diagnosed Jan. 4, 2007 with a very fast aggresive form of diffuse sclero. I'm sure all of my doctors would argue with this, but I have a feeling that it was too much kenalog too fast!

Keeping you in my thoughts. -TJ

#6 Sweet

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Posted 09 June 2007 - 10:02 AM

Hi Joe,

I have never heard of Lunesta being responsible for scleroderma. There are so many varying factors which you will see when you check out this link from the ISN on Causes of Scleroderma.

I hope this will help you.
Warm and gentle hugs,

Pamela
ISN Support Specialist
International Scleroderma Network (ISN)

#7 Elehos

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Posted 09 June 2007 - 12:25 PM

Hi Joe,

With lupus and sclero, I've found that I react severely to meds now, although you could have given me d-con years ago with no more than a burp afterwards. It could be that the sclero was already there, and your reaction to Lunesta was due to that. There was a post quite a while back about "triggers," and I don't remember off-hand if it was Americanmike that started it, but a lot of us seemed to have either numerous infections and surgeries for years before the sclero turned up. By any chance is that part of your history too? Not to say that's the cause, but just curious.

Best wishes to you,

Elehos

#8 Sherion

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Posted 09 June 2007 - 01:01 PM

Joe, I'm not sure if any medications brought on sclero for me. All I know is that I was a really sickly child, but for about 13 years before my diagnosis my life was a stress filled roller coaster. Symptoms seemed to have started about three years before I finally got the sclero diagnosis. The doctors really don't give you any reason as to why, it just happens. I truly think stress is a big factor. Just my opinion.

Sherion

#9 rlbrussell

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Posted 09 June 2007 - 05:39 PM

Triggers. What a great question. I was always as healthy as a horse and a very active technical climber. I always took really good care of my body being conscience of my nutrition and exercise. One morning I woke up with swallon hands and six months later I was diagnosed with Diffuse Sclero. I think for me it was just a case of very bad luck.
Rosa
Diffuse Sclero
dx Jan 2006

#10 LisaBulman

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Posted 10 June 2007 - 01:17 AM

Hi Joe,

I remember as a little girl always being sick with one thing or another. I had strep throat umpteen times until my tonsils were removed when I was 6/ When I was a little older I had constant urinary tract infections (UTIs) and then kidney infections with mono twice in high school. Not sure what my trigger was, but I have been on Ambien for about 4 years now and I don't think it has progressed my disease.

Hugs,

Lisa
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#11 kramer57

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Posted 10 June 2007 - 02:20 AM

I always had cold hands and feet, even as a child, got sick with bronchitis every winter. Age 16, depression and epilepsy, started meds. Age 17, developed gallstones and had gallbladder removed, acid reflux and trouble swallowing started 6 years later. Then asthma, arthritis. So I have no idea. I think my Sclero is genetic and has been showing itself from childhood, but it was just never recognized until this year. I don't know if it's surgery, or meds, or stress that made it really get bad - I couldn't say for sure when it started.

Karen

#12 barefut

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Posted 10 June 2007 - 07:00 PM

I suspect stress and pregnancy.

#13 WestCoast1

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Posted 11 June 2007 - 05:49 PM

I feel the same as Barefut, I started experiencing symptoms during the pregnancy with my second child.
*WestCoast*

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#14 Joe

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Posted 11 June 2007 - 06:30 PM

Thanks for the info everyone...I am sure there are triggers but I am also sure it is different for everyone. I think Genetics plays a role also. I found a distant cousin of mine also has it. I read that there is a high prevalence of SSc in certain Indian tribes too.

Joe

#15 ShawMJ

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Posted 12 June 2007 - 05:36 PM

Triggers huh,I think mine was chemicals that I handled when I was working in the enviornmental services at a local casino.Some of it was very strong and burned our eyes throat,etc.We complained enough that they started using some other kinds but I often see those same chemicals in other places as in Superstores.I was under a lot of stress as well.Whatever I will always blame it on that.Mary-La.

#16 Connie

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Posted 14 June 2007 - 08:27 AM

Hi there. I have often wondered about triggers. I started having symptoms of scleroderma and Lupus after I had a miscarriage. I already had two childern and had no problems. After the miscarriage I had two more childern and I continued to have the symptoms and it gradually got worse. I have wondered if it could have been the hormone changes that come with pregnancy. My first two childern were born when I was in my early 20's. I was in my late 30's when I had my miscarriage and last two children. Who knows.

Connie

#17 Sharonvandee

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Posted 20 June 2007 - 08:10 PM

I started getting syptoms to whilst I was pregnant with my forth child. Though the warning signs were there just before pregnancy the IVF clinic did a test that discover I had anticardiolipin anti bodies, when the pregnancy started to run into problem I was asked by a doctor if I had connective tissue problem. I told him I didn't know what he was talking about but after the pregnancy I continue to worsen and ealier this year the diagnosis came now we just need to work out how this will evolve for me.
Kindest Regards

Sharon

Diagnosis Scleroderma-crest, Scolliosis, Asthma, ILD, Plueral Fibrosis, GERD, Hiatus hernia, Anticardiolipin positive, ANA positive

a little bent and broken and almost beyond repair!

#18 oddone

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Posted 22 June 2007 - 10:48 PM

Don't know about a "trigger". My husband was diagnosed Oct 06(age 38), had a very close male friend (best friends in public school) diagnosed when he was 18.

Extremely WEIRD, as this seems to be a "womens' disease" with the stats being only 1 in every 7 patients with Scleroderma being male. I always tease him "What were you guys smoking behind the school, hoping you wouldn't get caught??" Haven't found any evidence of anything, but I'm wondering about "environmental" and combined with the luck (or bad luck as it seems) of their genetic pools.
Oddone - Spouse - 38 yr old Husband diagnosed October 2006, Diffuse Systemic Scleroderma
Normal PFT(July 06), ECG(Nov/06)