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Question For Those Of You With Centromere Ana Pattern


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#1 Tammy

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Posted 20 November 2007 - 07:03 PM

I was just wondering for those of you with a centromere ana pattern, have any of you had problems with tumors? If I am reading correctly (probably not though), the centromere is part of a chromosome which would mean that it has to do with cell division, right? If tumors are caused by improper cell division and death of cells, is it possible that tumors could be related to this? If so, and this is a "chicken or the egg question", would it be tumors causing the positive ana or the ana causing the tumors? :huh: I was just wondering!

Tammy

#2 Sweet

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Posted 21 November 2007 - 05:59 AM

Hi Tammy,

Unfortunately, I can't give you a very educated answer, but I can tell you I have the centromere ANA pattern and have never had problems with tumors. My rheumatologist is very informative and he's never mentioned this either.

Hopefully someone else will chime in with more information.
Warm and gentle hugs,

Pamela
ISN Support Specialist
International Scleroderma Network (ISN)

#3 Kim T

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Posted 21 November 2007 - 01:45 PM

I don't want to send incorrect medical advice but I think you're reading way too much into this. The ANA test is used to look for certain patterns they see under the microscope and which are identified with certain disorders. Each pattern is related to certain antibodies. Having the centromere pattern is associated with the antibodies that are associated with CREST. Nothing to do with your chromosomes and cell division.

Hope that helps,

Kim