Turmeric And Curcumin
Posted 28 January 2008 - 06:28 AM
Curcumin Inhibits the Progression of Fibrosis in an In Vivo Model of Scleroderma Lung Disease. Previous in vitro studies have revealed that scleroderma (SSc) and normal lung fibroblasts respond differently to curcumin, the major component of the Indian spice turmeric, and that these different responses are due to altered PKC epsilon signaling. Because curcumin is known to be non-toxic, these results suggest that curcumin may have therapeutic value in treating patients with SSc lung disease. Stanley Hoffman. ACR Conference Oct. 2003.
There are also a lot of interesting early studies from high quality sources regarding Turmeric's effect on Rheumatoid Arthritis and cancer. My husband sat with a physician from the NYU cancer institute who happened to be Indian on his commute to NYC. He decided to ask him if his wife's Trumeric consumption was crazy or not, and got 30 minutes full of the benefits and history of turmeric (on of the primary spices in curry). Anyway I have been taking it for the past two months (mixed with chocolate and pepper to improve absorption) and have definitively noticed some improvement in a number of symptoms including gastric and hand numbness.
My diagnosis is fairly recent and I started taking Hydroxychloroquine (Plaquenil) four months before starting the Turmeric, so there is really no way to know if the Turmeric helped. I will be interested in seeing of my lung function tests show any improvement but they will probably not be redone for another six months. I would love to know if anyone else is taking Turmeric and what their experience has been.
Posted 28 January 2008 - 06:26 PM
In India, there is widespread use of turmeric for its health benefits. I do not claim to have my improvements on turmeric, but I take quarter spoon of turmeric and one spoon of flaxseed powder mixed in juice every day. It might have contributed some of my improvements. You can buy turmeric at any Indian grocery stores for less than $5/lb.
Posted 29 January 2008 - 01:16 PM
Posted 31 January 2008 - 07:40 AM
I found a couple more articles from the medical database "PubMed". This first one (2007) shows its positive affects on skin diseases such as scleroderma and its positive affect on wound-healing.
Beneficial role of curcumin in skin diseases. Adv Exp Med Biol. 2007;595:343-57
The second one suggests a positive affect for treating scleroderma lung fibrosis.
Curcumin-induced apoptosis in scleroderma lung fibroblasts: role of protein kinase cepsilon. Am J Respir Cell Mol Biol. 2004 Jul;31(1):28-35
Sam, No they are not referring to cumino. Curcumin is an extract from tumeric, a very orange spice used in foods from India,
ISN Support Specialist
(Retired) ISN Assistant Webmaster
(Retired) ISN News Director
(Retired) ISN Technical Writer for Training Manuals
International Scleroderma Network (ISN)
Posted 01 February 2008 - 11:56 AM
Posted 06 February 2008 - 08:10 AM
It would have been nice if you could compare your reaction to the combination with any reaction you might have to a Turmeric only regime. Turmeric is supposed to help with intestinal inflammation, so I would be surprised if this was the culprit.
Posted 06 February 2008 - 01:33 PM
I would be interested in knowing how much turmeric we should use per day as well and what's the best way for absorption to take it?
Crawler....mixed with chocolate and pepper (how much of each please and do you mean chocolate as in a chocolate bar or chocolate powder like hot chocolate mix?).
Kamlesh, is the turmeric at an Indian store more pure that say at a grocery store in the spice bottles??
Posted 06 February 2008 - 08:07 PM
Turmeric found in US grocery stores may be similar to Indian grocery stores. Turmeric in Indian stores may be fresher and cheaper. We use turmeric in all vegetables and soups. I also take every morning along with Flaxseeds mixed in any juice. In India, they also use to stop bleeding from wound. Normally, about a Â½ teaspoon per person per day should be sufficient.
Turmeric is similar to ginger, it is vegetable and grows underground. It can be eaten raw, with little salt and lime.
Posted 07 February 2008 - 02:34 PM
Thank you. I was curious to know if it would have the same potency. Sounds like it might be. I am not near any Indian stores here either.