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Cellcept Vs. Imuran

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#1 peanut


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Posted 04 December 2006 - 04:56 PM

My doctor will be putting me on Imuran soon. I'm rather new to all of this am not sure what's the difference between Imuran and Cellcept. They're both immunosuppresents, but is one stronger or better than the other? What's the difference?

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my HMO makes me wear a helmet...

#2 janey


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Posted 05 December 2006 - 07:40 AM

I did a little reading on the mechanisms used by these two drugs in suppressing the immune system, but I needed a medical dictionary to really understand what I was reading. huh.gif So I'm not going to be much help here, but I'll try.

Yes, both Imuran and Cellcept are immunosuppresant, but they suppress the immune system in different ways. Indirectly, they both affect the production of T cells (from what I could gather). Here's a brief explanation of T cells that I got off the ISN T Cells page.

T cells are white blood cells that help stimulate an immune response to infections. In the thymus gland, lympohocytes are matured into T cells Sometimes T cells become overactive, which is suspected as being part of the process that leads to autoimmune diseases.

Since there are numerous causes to scleroderma, one immunosuppresant may work while another doesn't, so it's a matter of trying them out, so to say, until you find the one that works for you.

Good luck with the Imuran. I hope you see some positive results. Please let us know.

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Janey Willis
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International Scleroderma Network (ISN)