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MediQuest Therapeutics Submits Drug Application to FDA to treat Raynaud's Disease

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#1 Guest_Jude the Grouch_*

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Posted 12 May 2008 - 07:54 AM

MediQuest Therapeutics Submits Drug Application to FDA to treat Raynaud's Disease. MediQuest Therapeutics Inc. submitted a New Drug Application (NDA) to the U.S. Food and Drug Administration(FDA) for MQX-503, a topical formulation designed to treat Raynaud 's Disease. In 2007, patients enrolled in a confirmatory Phase III study of MQX-503, showed statistically significant improvements in their condition when treated with the therapy. Drugs.com. April 28, 2008. (Also see: Raynaud's)

#2 Karenlee


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Posted 13 May 2008 - 02:00 AM

Can I jump for joy yet or is it too soon? Lol! Imagine a topical for Raynauds?? One less pill to take is always reason for cellebration. Let's hope they don't drag their nice warm feet on this one eh? :D

#3 JudithL


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Posted 13 May 2008 - 04:52 AM

Much as I hate to rain on anyone's parade, I have to add a word of caution here. I participated in several phases of the clinical trials for this medication, which I believe will be marketed as Vascana. It had absolutely no impact on my Raynaud's symptoms. My understanding is the trials showed improvement for people with Raynaud's disease (primary Raynaud's) but not for people with Raynaud's phenomenon (secondary Raynaud's). I'd be interested in knowing if other forum members participated in the Vascana trials and, if so, if they noticed any improvement in their Raynaud's symptoms.

I recently participated in an early phase of the trials for the follow-on product to Vascana. Like Vascana, its active ingredient is nitroglycerin, but it's delivered in a solution that supposedly is absorbed more quickly into the skin.

#4 janey


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Posted 13 May 2008 - 06:28 AM

It's always good to hear someone's personal experiences in a trial! I'm sorry this one didn't work for you. As with any medication, it works for some but not for others.

Here is a link to the clinical trials results. It did include both primary and secondary Raynaud's patients.

A Multi-Center Placebo-Controlled “In-Life” Study of MQX-503 in Patients with Raynaud Phenomenon.

Big Hugs,
Janey Willis
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