Posted 26 August 2008 - 06:55 AM
Posted 26 August 2008 - 07:21 AM
Posted 26 August 2008 - 07:34 AM
Here are a couple of explanations in our section on Weight Gain with Prednisone. It's probably different for different drugs but with prednisone apparently it can be a combination of sodium retention. loss of potassium, and redistribution of body fat. Hope this helps.
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Posted 26 August 2008 - 09:03 AM
Posted 26 August 2008 - 09:44 AM
I have a friend in the business that did a paper on this. His findings were - on some medications, a person feels sedated and require more sleep. This results in less activity with fewer calories expended throughout the day. There is some evidence that patients choose to snack on carbohydrates, and this predisposes patients to gain weight. Some meds are associated with even more carbohydrate craving. Some patients have a significant increase in carbohydrate craving together with weight gain shortly after the beginning some meds.
Since patients gaining weight often say that they are not eating more, it is tempting to speculate that there may be a drug-induced lowering of the metabolism. He could only find one paper demonstrating such a change in metabolism. He noted that weight fluctuations reflect a balance between caloric intake and caloric expenditure. Thus, weight gain is due to positive energy balance, that may be explained by an increase in total calories consumed and/or a reduction in calories used by the body.
Hope that helped.
Posted 26 August 2008 - 12:40 PM
Thanks again, Sweet.