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Autoimmune Hepatitis


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11 replies to this topic

#1 marys

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Posted 18 October 2008 - 02:37 PM

Hi Everyone,

Its been along time since I've been here so hi all.I had a phone call from my Dr. and she said my Enzymes 4 times the normal so I saw her on Thursday and my GOT/AST 226 last month 28 and GPT/ALT 236 last month 40.How can it jump that fast?And most of all what does it mean?Also ALBUMIN 5.1 andCO2 33

I'm taking a bunch of meds. but she said that it could be the Methotrexate so I'm off that for 2 weeks until we do more test.Besides Methotrexate I was also on a prescription painkiller both for at least 2 years.Being honest I was drinking beers and cigarettes also so now I'm freaking out.

I've read on the internet that it might be AutoImmune Hepatitis or Toxic Hepatitis.Do you know anything about this?Has this happened to anyone else and what is your diagnosis's and can it heal on its own?I sure hope it isn't serious I'm having anxiety attacks.
I've been diagnosis'S with SLE,SJORGREN'S,RAYNAUD'S,INFLAMMATORY ARTHROPATHY,DDD,R/O MORPEA(I'm not sure what this is).Please reply if you can.

Thank you for listening,
Mary

#2 canon

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Posted 18 October 2008 - 05:15 PM

Marys,

Please take care of yourself. Some of the medications we take can be so toxic. We can't do what we used to do even if it is just for a bit. Keep seeing your doctors and don't let the diseases you have take over.

Keep you in my thoughts.

Judy
A happy heart is good medicine.

#3 jefa

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Posted 18 October 2008 - 06:59 PM

Hello, Mary

First of all don't panic. It is so easy to get wound up in all this information and get completely stressed out. Since you are seeing your doctor about this, continue to do this and ask these questions. It might be a good idea to write everything down in the form of questions for her. Be honest with her about the drinking and smoking. I am not a doctor, but I have read about methotrexate and know that you should not be drinking at all while taking it. Smoking and Raynaud's do not mix, so you should really try to get some help stopping smoking. Hepatitis can be tested for if it is a concern. SLE is Systemic Lupus Erythematosus and Sjogrens is another autoimmune disease which can exist on its own or alongside others. I have inflammatory arthropathy (inflammatory arthritis) as well as Raynaud's. I don't know what DDD means but R/O means rule out, so I don't know whether the note means that morphea needs to be ruled out or has been ruled out. Do make a list of questions for your doctor and let her know all of your concerns.
Warm wishes,
Jefa

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#4 LisaBulman

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Posted 19 October 2008 - 02:15 AM

Hi Marys,
A few years back I was in a drug study and the side effect of the medications was liver enzyme elevation. Well my liver numbers were fine all through the study and as soon as it ended I received the real medication. After 3 weeks it was clear that I had been on the placebo for the study because my liver numbers started to climb. I immediately stopped the medication but my numbers still went up and up and up. I think at their highest they were 350 and 544. Way out of range. It took about three years for them to finally come back down to normal. As Jefa said you should really try to quit smoking and not drink while on the methotrexate. Drink lots of water too to flush out your liver.

Please keep us posted.

Hugs,
Lisa
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#5 marys

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Posted 19 October 2008 - 02:55 AM

Thank you very much for the great info and advice.I can quit smoking no problem with that because I only smoke when I drink and seeing the liver count thats enough for anyone scarred the you know what out of me.

Lisa when the enzymes were elevated did they diagnosis's you with AH? Lisa what were you diagnosis's with the enzymes elevated?Did you smoke or drink? Because of the Sjorgren's I drink alot of water.
Wheb you have a positive SSA but negative B what does that mean Secondary Sjorgrens?I don't understand how it works.

DDD is Degenrative Disc Disease.I also have herniated disc from a car accident L-4 L-5and S-1and alot of Sciatica nerve pain.

The meds I take are Lyrica,Prednisone,Placquenil,Folic Acid,Prevacid,Baclefon,ans Norvasc.

Thanks again,
Mary

#6 marys

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Posted 21 October 2008 - 04:52 AM

Lisa I was wondering if you were diagnosis's with AH or what.How are you now with your liver still elevated or normal counts?

Thanks again,
Mary

#7 Clementine

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Posted 23 October 2008 - 06:01 AM

Mary,

Just wondering if you have found anything out about your liver panel tests.

I am in the middle of trying to figure out what is causing my liver enzyme elevations too.
Today, I had a few more specific liver lab tests done. Two were antibody tests, that help with the diagnosis of Primary Biliary Cirrhosis or Autoimmune Hepatitis. I will know more soon, in regards to how it's diagnose and will pass it on to you. I am wondering if AI Hepatitis can be drug-induced (Cellcept) or if it is independent, or both.

Congrats on quitting the smoking.

xo,
Clem

#8 GocartMoz

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Posted 23 October 2008 - 02:36 PM

Hi Mary,

I am chiming in on your post a little late, but we have a page here that might give you some interesting information on autoimmune hepatitis. Unfortunately, I don't know much about it myself, but you may find some info that helps you understand things a bit better. I hope it helps.

Hepatitis, Autoimmune

#9 marys

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Posted 25 October 2008 - 04:53 AM

Thank you all for responding.My next blood drawn is Thursday 30 and I can't wait because I can't take to much more of the anxiety I feel like I'm going to have a heart attack not knowing.Thank you for the post and I will check it out.Thanks

Clementine can I ask what your enzyme levels were.The main medication my rheumatologist is concern with is Methotrexate and the pain medication that I've been taking together for the last 1 1/2.Please let me know any information and I will do the same hopefully first of November.Good Luck with everything.

Take care and Thank you,
Mary

#10 marys

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Posted 27 October 2008 - 07:12 AM

I have to correct something. My tests are not 1 month apart. The last time I had my test was in April and was wondering if this will make a difference with the results. Hope to hear anything.

Thanks again,
Mary

#11 LisaBulman

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Posted 27 October 2008 - 01:58 PM

Hi Marys,
They did diagnose me with auto immune hep at the time. They said my liver was filled with "garbage cells". It took a long time (few years) for my numbers to come down to a normal state. I don't drink alcohol (very rarely maybe twice a year) and I don't smoke. I was drinking tons of water to flush it out.

Please keep us posted!

Hugs,
Lisa
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#12 Clementine

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Posted 28 October 2008 - 01:54 AM

Hello Mary,

My ALT and AST were about triple the high end of normal for 7 lab tests, and for a total of 6 weeks. Finally, last week's ALT and AST were within the normal range. I stopped taking Cellcept so we are in the process of trying to figure out if that was the problem. I am currently waiting on tests results for the mitochondrial antibody (AMA) and smooth muscle antibody (SMA) labs, which helps diagnose autoimmune hepatitis or primary biliary cirrhosis (PBC).

The first thing my nurse asked me when my enzymes were elevated was if I was taking any herbal medications, which I don't.

Please let me know what you find out. I will post as soon as I get my other lab results.

Have a good day,
Clem