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Diagnostic value of anti-topoisomerase I antibodies


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#1 Jeannie McClelland

Jeannie McClelland

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Posted 23 February 2009 - 09:17 AM

Diagnostic value of anti-topoisomerase I antibodies in a large monocentric cohort. Diagnosis and risk assessment of scleroderma patients can be supported by the detection of anti-topo I antibodies. Signal intensities as obtained by LIA or ELISA can be used as a surrogate marker for fibrosis, active disease and worse prognosis. K. Hanke. Arthritis Research & Therapy 2009, 11:R28. (Also see: What are Antibodies?)

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