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methotrextrate and yeast infection

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#1 ozzy69


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Posted 09 April 2009 - 08:25 AM

Does anyone know if methotrextrate causes Yeast Infection?

#2 Amanda Thorpe

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Posted 09 April 2009 - 09:47 AM

Hello Ozzy69

I had a look at side effects and one can be low resistance to infection. It may be that the MXT has lowered your resistance and as a result the yeast infection has come along. I am sorry you have this as any woman knows it's the pits with the itching, burning, stinging etc. etc.

I hope you get relief soon and take care.

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#3 ozzy69


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Posted 09 April 2009 - 11:00 AM

Thanks Amanda,

They also upped my hormones a couple weeks ago. The hormone change and the lower resistance probably has caused the yeast infection. My doctor gave me a script last week that was a pill for the yeast infection. It did not seem to work.. I tried new meds today, hopefully I will get some relief soon.

Nina Lynn

#4 janey


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Posted 09 April 2009 - 11:44 AM

Sorry to hear about the yeast infection. Believe it or not, I've only had a couple of them in my lifetime. One was during the second week I was on Imuran and the other was during the third week I was on oral Cytoxan. I was on Methotrexate for 3.5 years with no infection. Amanda makes a lot of sense in saying it's probably due to your suppressed immune system. The important thing is to get it under control and get rid of it. You don't want to ignore if that were even possible.

Hope your meds start to work.

Big Hugs,
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#5 Purr


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Posted 09 April 2009 - 12:36 PM

Prednisone will do it. I take that along with MTX.

Love makes the world go around!

#6 ozzy69


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Posted 09 April 2009 - 02:00 PM

Thanks Christy and Janey,

The only time I ever had yeast infections are after large doses of antibotics or I got one when I was pregnant with one of my boys. I did take antibotics about 4 weeks ago for a bladder infection.

It seems like I always have something going on.. I just hope this is not going to become something that happens often. It does not feel really good! LOL

I am not on Prednisone.

Thanks again,
Nina Lynn

#7 WestCoast1


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Posted 09 April 2009 - 02:58 PM

Hi Amanda,

Yikes, I am so sorry to hear that you have to go through that! Men are so lucky some times! My doctor once told me that if the medication does not work for yeast, than it's not yeast and that means a trip to the doctor to get a better idea of what is going on.

I hope that you are able to take care of it ASAP!



#8 lizzie


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Posted 09 April 2009 - 10:32 PM

Hi Nina Lynn, coincidently I have just started yesterday with what I presume to be yeast infection . I have had them several times over the last few years. I have previously had culture taken by the doctor when I experienced the same symptoms before and that confirmed a yeast infection. The treatment is generally a two pronged attack- oral tablet and vaginal pessary, and that seems to work for me.

I put this latest attack down to having antibiotics for a urinary tract infection a couple of weeks ago, but in the past they don't always seem to be related to anything in particular. I start methotrexate in the next week or two so hope that it doesn't cause yeast infection.


#9 Jeannie McClelland

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Posted 10 April 2009 - 04:21 AM

Hi Ladies,

Methotrexate doesn't cause yeast infections, but because it is used as an immunosuppressant when treating scleroderma, a side effect is decreased resistance to opportunistic infections.

The National Institutes of Health's Medline Plus has a really good page on Yeast Infections. Don't forget that thrush is also a yeast infection. You can have a yeast infection in your esophagus, blood, just about anywhere. I think most of us tend to regard a yeast infection mostlyas a nuisance, but it can be serious if occurs in the bloodstream or esophagus.

This is probably one of those cases where it's better to be safe than sorry and see your doctor. <_<

Big hugs,
Jeannie McClelland
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