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Diabetes types

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#1 betty32506


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Posted 04 October 2009 - 08:04 AM

I wasn't sure this subject was addressed on this site. When I found Janey's page thought perhaps it is.

Diabetic research shows an increasing need to know the difference in types of diabetes. I consider myself LADA on the basis of a positive GAD 65 test, I am not overweight, and have several other autoimmune problems. I was in my late 60's when glucose problems began to show up. I began cutting carbs and controlled it well for a few years. I didn't note dates so am unsure about specific dates. I began to have digestive problems, later diagnosed as gastroparaesis and asked my general practitioner for meds so that I could put the carbs back in my diet. That was 3-4 years ago. I now take Metformin, Ameryl and for bolus Starlex. My A1Cs run around mid 5s. My BMI is 18.6. C-Peptide mid range. I am now 76.

Now for the questions. Is that enough information to know I am LADA? Would the C-Peptide being in mid range indicate that the problem is not glucose resistance? Is a positive GAD 65 test on 1 GAD testing enough or does it need to be repeated for verification? What other test should be done to rule out insulin resistance? On the diabetic forums I conclude that the older a person is when the glucose problems shows up the slower it progresses thus making it a longer period of time that it can be controlled without insulin.

I read on this site that many times doctors are a problem and cannot always be taken as knowing what they should. That is why I left the Endo and see my general practitioner. He doesn't claim to know all the intricacies and has no problems with my input. Multiply that by several times and you can come up with my level of trust of doctors in regard to diabetes. I raised a diabetic child, now 50, and found it necessary to control things myself. The diabetes communities now can't even agree on many aspects of managing diabetes.

Comments appreciated.


#2 smac0719


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Posted 04 October 2009 - 12:14 PM

Wow Betty. I was diagnosed as diabetic several years ago and at the time I believed it because my glucose levels were elevated and my A1C was over 6. However, you mention tests and terms that I have never heard before. After a year of trying Metformin and Byetta we discovered that the medications dropped my blood sugar too low so I just controlled my diet better to help reduce my elevated numbers. I can now say that my glucose levels are great and my A1C has been under 6 for a couple of years. I told my doctor I really didn't think I was diabetic anymore or maybe never was, but she still says I am because my fasting glucose level has been consistently above 100 with 111 being the highest.

I have read that other factors can increase glucose levels so my jury is still out on the diabetes diagnosis. I have enough medical issues to keep on the list so if I can eliminate one I'd really like to do that.

I am curious to see the responses from others who know about LADA, the GAD test and C-Peptide. I am going to do some research too and inquire about these with my primary the next time I see her.
I may have Scleroderma, but Scleroderma doesn't have me!

#3 Kamlesh


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Posted 04 October 2009 - 01:31 PM


I have type 2 diabetes for last 15 years and Scleroderma. My primary physician does not want my A1C to go below 6 as there is more danger sugar going too low. I maintain my A1C between 6 to 6.5 and morning glucose below 100.
Kind regards,


#4 janey


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Posted 05 October 2009 - 03:47 AM

I did find this abstract in the medical database (PubMed).

Latent Autoimmune Diabetes in Adults. Here's a couple of items from this abstract.

"Among antibodies, GADA is the most frequently occurring autoantibody, followed by ICA. The natural course of these patients shows that C peptide will decrease with time in parallel with the curve for C peptide in classical type 1 diabetic patients...Our recommendation is that all patients be tested for pancreatic islet autoantibodies at diagnosis of diabetes..."

If you really want to check out what's out there, here is a link to PubMed. Do a search on LADA diabetes antibodies and you'll get several abstracts.

I hope this information helps. Looks like I'll be adding more to the diabetes pages on LADA.

Big Hugs,
Janey Willis
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