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Coumadin to control calcinosis

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#1 JBG


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Posted 07 January 2010 - 11:09 AM


I was wondering if anyone has heard of treating calcinosis with coumadin.

I'm scheduled for surgery next Friday to remove a large calcium deposit from the ball of my foot. I also have several other calcium deposits in my fingers and had surgery in the past to remove calcium from my wrist and forearm. Since calcium is forming more frequently in my body, my rheumatologist [today] suggested that I start coumadin for 6 months sometime after I have my foot surgery.

What do you think? Any feedback would be appreciated.


#2 Amanda Thorpe

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Posted 07 January 2010 - 02:39 PM

Hello JBG

I can't comment on coumadin (warfarin)or calcinosis because I don't have it. What I can do is direct you to the information on this site about calcinosis and warfarin.

It says:

While warfarin, colchicine, probenecid, bisphosphonates, diltiazem, minocycline, aluminum hydroxide, salicylate, surgical extirpation, and carbon dioxide laser therapies have been used, no treatment has convincingly prevented or reduced calcinosis.

Hopefully others with calcinosis will join in soon.

Take care.
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#3 janey


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Posted 11 January 2010 - 11:35 AM

I personally am not familiar with the treatment of calcinosis with coumadin (warfarin) and based on a couple of abstracts in the calcinosis treatment section that Amanda linked you to, a study from 2004 states "Low dose warfarin may serve as an effective treatment for calcinosis in a selected group of patients who have small and relatively new onset calcinosis. This treatment does not prolong the coagulation of blood and there is no increased tendency for bleeding" PubMed. Ann rheumatologist Dis. 2004 Oct;63(10):1341-3.

I did some research to see if there have been any new findings since 2007, but haven't found anything that changes what is already in this section. It does appear that surgery is the standard treatment and that medications as treatments are generally ineffective. Hopefully they will find something soon. I'm sure surgery is not fun. Hope all goes well on Friday.
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#4 JBG


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Posted 11 January 2010 - 12:07 PM

Thanks so much for your replies. I really appreciate it.