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Exercise in systemic sclerosis intensifies systemic inflammation and oxidative stress


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#1 Jeannie McClelland

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Posted 26 February 2010 - 11:33 AM

Exercise in systemic sclerosis intensifies systemic inflammation and oxidative stress. Although exercise capacity is impaired in patients with SSc, physical activity intensifies the already increased basal levels of systemic inflammation and oxidative stress. These data support the concept of a role for systemic inflammation and oxidative stress in the ongoing systemic effects of SSc. H Harðardóttir. (PubMed) Scand J Rheumatol. 2010;39(1):63-70. (Also see: Oxidative Stress)

This item was posted in the ISN Newsroom. Check the Newsroom every day for the latest scleroderma medical and support information.
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#2 janey

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Posted 26 February 2010 - 12:20 PM

Jeannie,
I found this one very interesting. It kind of explains a lot of what I read about exercise and chronic illness, particularly connective tissue - moderation. My doctors are always encouraging me to exercise, but within limits. I use to be a maniac, but now I do just enough to make me feel good physically and emotionally, but my body always tells me when I've over done it. So I guess the important thing is to "listen to your body!"

Thanks for the article!
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#3 pawndy

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Posted 26 February 2010 - 04:31 PM

This is interesting. Maybe this explains why when I have a busy day; it takes me three days rest to recoup.

Thanks for the information.

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#4 Shelley Ensz

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Posted 01 March 2010 - 06:52 AM

I'm copying this News Forum article to the Main forum, since I think many of us will want to read about it or discuss it.
Warm Hugs,

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The most important thing in the world to know about scleroderma is sclero.org.

#5 Joelf

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Posted 01 March 2010 - 10:08 AM

A very interesting article, Jeannie; especially for an exercise junkie like me!!! :rolleyes:

I really wish I could do the same level of exercise that I did pre-Sclero; sadly it ain't gonna happen!!! ;)

I still go to the gym every day but I have toned the intensity down quite a lot; as Janey says moderation is the key!! :)

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#6 Sharon T

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Posted 01 March 2010 - 12:30 PM

this is very interesting. One of the things I've found very frustrating is that my rheumatologist says I should exercise as hard as I can, even though I have pulmonary hypertension at stress. I've always thought that since the PAH is a dangerous condition, and mine only manifests when I'm exercising, shouldn't that mean that too much exercise is not good? This article seems to indicate that, but I'm not able to really determine how much exercise is too much. Some days I'm able to do more with less effort than others. Are there are concrete guidelines out there for the amount of exercise that remains beneficial without creating additional inflammation? Aaargh - nothing is easy!

Sharon T
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#7 Jeannie McClelland

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Posted 01 March 2010 - 05:42 PM

Adds a whole new meaning to "going for the burn", doesn't it? Of course it is important to talk to your doctor(s) about any exercise limitations or recommendations, but I exercise to capacity. For me, probably like everyone else, that varies from day to day so I don't set myself hard and fast goals. What I don't want to do is set myself up for exercise failure because then I might just give up exercising at all. <Sigh> Exercising is important to my mental well-being, so I try to do something every day, even if it is only extra trips up and down the stairs.

Warm hugs,
Jeannie McClelland
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#8 barefut

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Posted 02 March 2010 - 01:03 PM

I am forwarding this article to my rheumatologist and pulmonologist. I think they would find it interesting too.

#9 enjoytheride

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Posted 02 March 2010 - 01:37 PM

Finally- as a confirmed couch potato (ie sweating is an indication that your body is crying out in pain) I finally have something I can cite as scientific evidence of the benefits of NOT exercising. :)
At least not really hard anyway..............

#10 Tammy

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Posted 02 March 2010 - 04:29 PM

Hmmm, could expalin why the ab lounger was causing so much joint pain! :lol:

#11 CraigR

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Posted 03 March 2010 - 09:52 AM

I can't say this is news to me - The surest way for me to go into a major inflammation attack is physical exercise.

Craig

#12 Honey

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Posted 04 March 2010 - 06:10 AM

As a fitness instructor and personal trainer, I found right away that I could not do any of the strength or cardio classes I was teaching. Now my instructing is yoga 5x weekly and line dancing 2x weekly.

I am happy to know that what I am missing is necessary for me. But, of course, I don't think this gives us license to do nothing in the form of exercise. I believe all aspects of my being (mind, body and spirit) are the better due to the yoga practice. It is a gentle yoga without the infringement on my faith or anyone else's. There is a beautiful coming together with each other in the class setting as well as individually.

Kindest regards,
HONEY