ISN: Romanian Version

Sistemica: Difuza

Aceasta pagina a fost editata de Shelley Ensz, medical editata de Dr. Dolores Vázquez-Abad, traducere si adaptare Krista. Vezi Disclaimer.
Ce este Scleroderma Difuza
Difuza fara Afectarea Pielii
Afectiuni ale Organelor Interne

Ce este Scleroderma Difuza?

Scleroderma Sistemica Difuza mai este cunoscuta si sub denumirile: Scleroderma (SD), Scleroza Difuza, Scleroderma Cutanoasa Difuza, Scleroza Sistemica, Scleroza Progresiva Sistemica.

De asemenea include si forma Scleroderma Sans Scleroderma ( scleroderma fara scleroderma).


Scleroderma Difuza, este diagnosticata atunci cind pielea este afectata, in punctele de referinta. Dar sint doua puncte de referinta:

1. The American College of Rheumatology defineste punctul de referinta de la incheietura miinii.

2. Dr. LeRoy defineste punctul de referinta din zona coatelor

Probabil speriati, pacientii cu afectiuni ale pielii intre cot si incheietura palmei, pot primii diagnosticul: Scleroderma Sistemica Difuza sau Scleroderma Sistemica Limitata.

Aici diagnosticul depinde de care dintre punctele de referinta il ia in consideratie medicul respectiv.

Diagnosticul este clinic, si nu necesita neaparat teste de laborator, sau alte teste speciale.

Scleroderma Sistemica Difuza, fara Afectiunea Pielii

In unele cazuri Scleroderma Sistemica Difuza, nu afecteaza pielea sau incheieturile, si afecteaza doar tesuturile conective ale sistemului digestiv, sau al altor organe interne.

In absenta pielii afectate, care este un fapt vizibil, atunci se pune diagnosticul : Scleroderma Sans Scleroderma, ceea ce inseamna, "Scleroderma Difuza, fara Scleroderma" (fara afectiunea pielii)

In cazul Scleroderma sans Scleroderma fenomenul Raynaud poate sau nu sa fie prezent.

Afectiuni ale Organelor Interne

Organele interne sunt afectate in acest caz: pulmonar (fibroza pulmonara) ; renal, si/sau cardiac (inima), si/sau gastrointestinal.

In testele de laborator, anticorpii antinucleari (ANA) pot fi prezenti (dar nu necesar) (Scl-70, ACA.). Vezi: Scleroderma Symptoms and Treatments (engl.)


Cam 95 % din pacientii cu Scleroderma Sistemica Difuza prezinta in faza de inceput, intarituri ale pielii, special in zona miinilor, a bratelor si a fetei (acestea fiind urmarea fibrozarii tesuturilor). Afectiunea organelor interne, se poate echivala direct proportional cu cit de mare este zona pielii afectata.

In mod normal, afectiunea pielii incepe cu zona degetelor., ca apoi sa cuprinda palma, bratul.

Atunci cind este afectata zona bratului, incep sa apara afectiuni in zona picioarelor, si in unele cazuri, pe piept si abdomen. Intariturile pielii, apar in ambele parti ale corpului, si sunt simetrice. Poate fi afectata si pielea fetei si a gitului. Vezi : Scleroderma Photos (engl.).


(1) Paper for ACR criteria: Subcommittee for Scleroderma criteria of the American Rheumatism Association diagnostic and therapeutic criteria committee. 1980. Preliminary criteria for the classification of systemic sclerosis (Scleroderma). Arthritis Rheum. 23,581:590.

(2) Paper for Le Roy criteria: Kahaleh MB, Sultany GL, Loadholt CB. Smith EA, Huffstutter JE, and LeRoy EC. 1986. A modified Scleroderma skin scor method. Clinical & Experimental Rheumatology. (4):367-369.

Krista Lurtz

KristaPovestea Mea: Krista Nu este prea usor, sa incepi sa-ti scri propria istorie, in asemenea situatie.

De ce? Pentru ca habar nu am daca sa scriu despre Krista de acum citiva ani, sau Krista cea de acum. Da, sunt tot eu. Dar sub o altaforma fizica…

Povestea Mea: Krista (engl.) I promised Shelley that some day, I would try to write my "real" story. It's been some time since that day. I tried, yes, I did. But, there's something which kept me from doing it…

To Krista: Global Outreach Excellent Award

SWA Global Outreach Excellence AwardThis award from the Scleroderma Webmaster's Association was given to Krista Lurtz, ISN Romanian Translator, for her excellent global outreach efforts.

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