| Localized Scleroderma: Linear |
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| Parry-Rombergs Syndrome |
| This page was written by Shelley Ensz, and has not yet been medically edited. See Disclaimer. |
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| Overview |
| Parry-Rombergs Syndrome, is also known as Progressive Hemifacial Atrophy or HFA. It may be the same as Linear Scleroderma affecting the face. (Also see: Linear Scleroderma) |
| Classification |
| En coup de sabre morphea and Parry-Romberg syndrome: a retrospective review of 54 patients. En coup de sabre morphea and Parry-Romberg syndrome frequently coexist and are likely both variants of morphea. Bilateral disease is more common than previously reported. The efficacy of antimalarials and methotrexate in the treatment of these diseases remains unclear. PubMed. J Am Acad Dermatol. 2007 Feb;56(2):257-63. (Also see: En Coup de Sabre and Morphea) |
| Plaque-type scleroderma associated with linear and oesophageal features and facial and extra-facial hemiatrophy. The combination of several sub-types of scleroderma and facial and extra-facial hemiatrophy in the same patient may indicate that these entities actually represent different spectra of the same disease. PubMed. Ann Dermatol Venereol. 2007 Jan;134(1):68-71. (Also see: Morphea ) |
| Complications of Parry-Rombergs Syndrome |
| Neuroretinitis, Parry-Romberg syndrome, and scleroderma. The authors report a new case of progressive hemifacial atrophy (Parry-Romberg syndrome). They emphasize the rarity of this disease, its etiology, which remains controversial, the diversity of its ophthalmologic manifestations, and its relations with scleroderma and autonomic nervous system disorders are discussed. Acute neuroretinitis remains rare and its pathogeny is unknown. PubMed. J Fr Ophtalmol. 2005 Oct;28(8):866-70. |
| Treatments for Parry-Rombergs Syndrome |
| Beneficial effect of immunosuppressive drugs on Parry-Romberg syndrome. We observed beneficial effects of immunosuppressive agents on neurologic lesions in particular in a patient with PRS who presented with immunoinflammatory findings and neurologic involvement, apart from cutaneous manifestations. PubMed. South Med J. 2005 Sep;98(9):940-2. |
| Progressive hemifacial atrophy with linear scleroderma. We think that linear scleroderma of childhood and hemifacial atrophy have considerable clinical overlap and these two syndromes appear to be manifestations of the same or related pathogenic processes. Recently, the beneficial effects of 1.25-dihydroxyvitamin D3 (calcitriol) were reported in adults and in children with linear scleroderma. Our result indicates that calcitriol may be an effective agent for treating localized scleroderma in children. PubMed. Pediatr Dermatol. 2005 Sep-Oct;22(5):436-9. |
| Parry-Rombergs Patient and Caregiver Stories |
| Alicia B: Localized Morphea with possible Parry Romberg Syndrome The doctor kept saying something had eaten away at all the fatty tissue and the muscles which left it just skin, blood, bone, and nerve so when you look at it, it looks like I have dirt on my face and a gaping hole to go with it... |
| Jessica G: Parry-Rombergs Syndrome By the time I was about five years old, the disease had already disfigured my left side drastically. I have had over fifty operations and surgical procedures for Romberg's.... |
| Mary B: Scleroderma En Coup de Sabre I feel like it is tearing my head open. Sometimes I get headaches, and I believe it is because of this illness... |
| Also see Linear Scleroderma Patient and Caregiver Stories... |
| Also See |
| Causes of Scleroderma. ISN. |
| Juvenile Scleroderma. ISN. |
| Scleroderma Photos. Pictures of scleroderma symptoms. |
| Submit your Parry-Rombergs Syndrome story. ISN. |
