Over 2,200+ pages in 22 languages!
 
What is Morphea?
The most important thing to know about morphea is that it is very different from the systemic forms of scleroderma, and it is never fatal.
Overview
Types of Morphea
Juvenile Scleroderma
Associated Conditions
Causes of Morphea
Complications of Morphea
Diagnosis
Photos
Research Registry
Treatments
Patient and Caregiver Stories
Overview

Morphea Scleroderma on LegMorphea scleroderma usually begins as patches of yellowish or ivory-colored rigid, dry skin. These then become hard, slightly depressed, oval-shaped plaques which usually have a whitish or yellowish center surrounded by a pinkish or purplish halo.

Morphea is most commonly found on the trunk, but can occur anywhere on the body. About 75% of the time it affects only the skin or underlying muscles and joints.

Types of Morphea
The most common type of morphea is a simple plaque-type, which affects only the skin and not the underlying tissues. It typically begins fading within about 3-5 years after onset, even without any treatment at all. Deeper, fast-spreading, cosmetically apparent, or different forms of morphea require early diagnosis and, preferably, treatment by a scleroderma expert. The rare types of morphea include:
Bullous Morphea
Deep Morphea
Dermatitis Artefacta
Generalized Morphea
Guttate Morphea
Keloid Morphea
Morpheaform or Basal Cell
Morphea Profunda (Subcutaneous)
Pansclerotic Morphea
Morphea, also known as localized scleroderma, is a disorder characterized by thickening and induration of the skin and subcutaneous tissue due to excessive collagen deposition. Morphea subtypes are classified according to their clinical presentation and depth of tissue involvement; they include plaque-type, generalized, linear, and deep varieties. eMedicine 2006.
Morphea scleroderma and its variants are also known as atrophoderma of Pasini and Pierini, bullous morphea, circumscribed scleroderma, deep morphea, disabling pansclerotic morphea, en coup de sabre, eosinophilic fasciitis, generalized morphea, guttate morphea, keloid, keloidal, or keloid-like morphea, linear morphea, localized scleroderma, morphea profunda, nodular morphea, pansclerotic morphea, plaque-type morphea, progressive hemifacial atrophy, progressive facial atrophy, Parry Rombergs, Shulman's syndrome, and subcutaneous morphea.
Localized Fibrosing Disorders: Linear Scleroderma, Morphea, Regional Fibrosis. Localized fibrosing disorders include several clinical and histopathological conditions that are similar to the skin involvement of systemic sclerosis, but the systemic features are absent. Localized fibrosing disorders can be classified into several subtypes that include morphea, generalized morphea, and linear scleroderma, in which facial involvement is termed en coup de sabre. eMedicine.com. 11/07/06. (Also see: Types of Scleroderma and Localized Scleroderma)
Juvenile Scleroderma
Juvenile Scleroderma. When any form of scleroderma begins during childhood (including morphea) it is also called childhood or juvenile scleroderma. (Also see: Types of Scleroderma)
What is Juvenile Scleroderma?
Juvenile Scleroderma Books
Juvenile Scleroderma Experts
Juvenile Scleroderma Research
Prognosis
Patient and Caregiver Stories
Associated Conditions
Overview of Associated Conditions
Additional Symptoms
Autoimmune Conditions
Cancer: T-Cell Lymphoma
Infections
Melanonychia
Skin Conditions
Systemic Scleroderma
Causes of Morphea
Autoimmunity
Cancer, Lymphoma
Dendritic Cells
Genetics
Infections
Borrelia Burgorferi
HTLV-1 Infection
Toxoplasma Gondii
Medications
Valproic Acid
Radiation
Solvents, Organic Solvents
Complications of Morphea
Plaque-type scleroderma associated with linear and oesophageal features and facial and extra-facial hemiatrophy. The combination of several sub-types of scleroderma and facial and extra-facial hemiatrophy in the same patient may indicate that these entities actually represent different spectra of the same disease. PubMed. Ann Dermatol Venereol. 2007 Jan;134(1):68-71. (Also see: Linear Scleroderma)
Morphea of the breast. Two case reports. Morphea is a recognised sequelae of radiotherapy which should be distinguished from sclerotic recurrence of the original tumour. Surgical excision is possible in certain patients. PubMed. J Plast Reconstr Aesthet Surg. 2006;59(10):1114-7.
Diagnosis of Morphea
Diagnosis of Morphea.Morphea is usually diagnosed by clinical examination. The diagnosis is sometimes confirmed with blood tests, skin biopsies, or other methods. ISN.
Morphea is a Clinical Diagnosis
Photos of Morphea
Antibodies/Blood Tests
Computerized Skin Score (CSS)
Skin Biopsy for Morphea
Infrared Thermography
Laser Doppler Flowmetry
Skin Biopsy
Ultrasound
Photos of Morphea
ISN Photo Repository: Morphea Photos. ISN.
Research Registries
First U.S. Morphea Registry and DNA Repository for both Adults and Children Established. Dermatologists at University of Texas Southwestern Medical Center are establishing a DNA repository aimed at people with morphea. They will collect information about other health conditions present, collect information about family history, and collect blood and skin samples to further define the genes associated with morphea and the genetic faces of morphea. Southwestern Medical Center. 05/31/07.
Treatments for Morphea
Overview
Scleroderma Experts
Apligraf for Bullous Ulcers
Bosentan (Tracleer)
Endermology or LPG
Imiquimod Cream
Laser
Methotrexate and Glucocorticoids
Phototherapy, UVA, PUVA
Tacrolimus Cream
English Morphea Patient and Caregiver Stories
(English) Morphea Patient and Caregiver Stories (Main Listing). ISN.
Italian Morphea Patient and Caregiver Stories
(Italiano) Morphea Storia. ISN.
Spanish Morphea Patient and Caregiver Stories
(Español/Spanish) Morfea Historia. ISN.
Keep on Surfing!
Go to Associated Conditions
Contact ISN. We are a full-service nonprofit agency.
Email: isn@sclero.org or
Post in Sclero Forums!
International Scleroderma Network (ISN)
7455 France Ave So #266
Edina, MN 55435-4702
USA
Toll Free Hotline in U.S.
1-800-564-7099
Direct Line
1-952-831-3091 (U.S.)
(We are also known as the Scleroderma from A to Z web site.)
© Copyright 1998-2008 International Scleroderma Network
All Rights Reserved