| Systemic Sclerosis: Scleroderma in Overlap, MCTD, UCTD |
| This page was written by Shelley Ensz and has not yet been medically edited. See Disclaimer. |
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| Overview |
| Scleroderma, or scleroderma symptoms, can occur in overlap with other illnesses. |
| Scleroderma in Overlap |
| Scleroderma in Overlap. When Systemic Sclerosis (in either the Limited or the Diffuse form) appears in conjunction with features of one or more other connective tissue diseases (such as Systemic Lupus Erythematosus, Polymyositis, Dermatomyositis) it is called "overlap." ISN. |
| New Systemic Sclerosis Classification Created. One in five patients with clinical symptoms characteristic of systemic sclerosis do not fit into the popular classification scheme that divides the disease into the diffuse and limited cutaneous subtypes, according to Dr. Thomas Krieg. B. Jancin. Rheumatology News. Volume 7, Issue 9, Page 27 (September 2008) (Also see: Types of Scleroderma and Undifferentiated) |
| Connective Tissue Disease (CTD) |
| Connective Tissue Disease (CTD). Connective tissue diseases include systemic lupus erythematosus, rheumatoid arthritis, scleroderma, polymyositis, and dermatomyositis. ISN. |
| Mixed Connective Tissue Disease (MCTD) |
| Mixed Connective Tissue Disease is an overlap of clinical features of systemic lupus ertythematosus, systemic sclerosis, and polymyositis, along with very high ribonucleoprotein autoantibodies, but without antibodies for other specific autoimmune diseases. ISN. |
| Multiple Autoimmune Syndrome (MAS) |
| Multiple Autoimmune Syndrome (MAS) is the coexistence of three or more autoimmune diseases. At least one of them is usually a skin disease, such as psoriasis or scleroderma. ISN. |
| Undifferentiated Connective Tissue Disease (UCTD) |
| Undifferentiated Connective Tissue Disease (UCTD). When a person has symptoms of various connective tissue diseases without meeting the full criteria for any one of them, it is often called Undifferentiated Connective Tissue Disease. ISN. |
| Shared Autoimmunity |
| Shared Autoimmunity is a rather loose term. It variously refers to autoantibodies, symptoms, or presence of autoimmune diseases within the same patient or within several or more members of the same family. ISN. |
| Overlap Patient & Caregiver Stories |
| Andi P: UCTD and Possible Scleroderma It is believed that I do have an autoimmune disease they are not sure if it is systemic or not, but I know what I live through on a daily basis... |
| Angela S: Overlap Syndrome I am twenty-five years old and I was diagnosed with polymyositis and scleroderma, rheumatoid arthritis, mitral valve prolapse, a heart murmur, and pericarditis... |
| Annette G: MCTD, Systemic Scleroderma, Chronic Kidney Disease, CFS, Fibromyalgia, Trigeminal Neuralgia, TMJ People think that because I am a nurse I have all the answers. Well guess what? I don't... |
| More Overlap Patient and Caregiver Story Listings... |
