|Overview of Polyautoimmunity
Scleroderma in Overlap
Connective Tissue Disease (CTD)
Mixed Connective Tissue Disease (MCTD)
|Multiple Autoimmune Syndrome
Undifferentiated Connective Tissue Disease (UCTD)
Overlap Patient and Caregiver Stories
Overlap connective tissue disease syndromes. Overlap Syndromes (OSs) have been defined as entities satisfying classification criteria of at least two connective tissue diseases (CTDs) occurring at the same or at different times in the same patient. Autoimmun Rev, 2012 Jun 26.
Introducing Polyautoimmunity: Secondary Autoimmune Diseases No Longer Exist. Polyautoimmunity is a term that can group all the taxonomy terms referring to coexistence of well-defined autoimmune diseases (ADs) in a single individual because some of the terms previously used are confusing and exclude various associations. NCBI. Autoimmune Dis, 2012; 2012: 254319. (Also see Multiple Autoimmune Syndrome)
Scleroderma in Overlap. When Systemic Sclerosis (in either the Limited or the Diffuse form) appears in conjunction with features of one or more other connective tissue diseases (such as Systemic Lupus Erythematosus, Polymyositis, Dermatomyositis) it is called "overlap." ISN.
Overlap with Lupus
|Overlap with Myopathies
Case Reports of Overlaps
Mixed Connective Tissue Disease is an overlap of clinical features of systemic lupus erythematosus, systemic sclerosis, and polymyositis, along with very high ribonucleoprotein autoantibodies, but without antibodies for other specific autoimmune diseases. ISN.
|MCTD and Scleroderma|
Multiple Autoimmune Syndrome (MAS) is the coexistence of three or more autoimmune diseases. At least one of them is usually a skin disease, such as psoriasis or scleroderma. ISN.
Undifferentiated Connective Tissue Disease (UCTD). When a person has symptoms of various connective tissue diseases without meeting the full criteria for any one of them, it is often called Undifferentiated Connective Tissue Disease. ISN.
Shared Autoimmunity is a rather loose term. It variously refers to autoantibodies, symptoms, or presence of autoimmune diseases within the same patient or within several or more members of the same family. ISN.
Andi P: UCTD and Possible Scleroderma It is believed that I do have an autoimmune disease they are not sure if it is systemic or not, but I know what I live through on a daily basis...
Angela S: Overlap Syndrome I am twenty-five years old and I was diagnosed with polymyositis and scleroderma, rheumatoid arthritis, mitral valve prolapse, a heart murmur, and pericarditis...
Annette G: MCTD, Systemic Scleroderma, Chronic Kidney Disease, CFS, Fibromyalgia, Trigeminal Neuralgia, TMJ People think that because I am a nurse I have all the answers. Well guess what? I don't...
SCLERO.ORG is the world leader for trustworthy research, support, education and awareness for scleroderma and related illnesses, such as pulmonary hypertension. We are a service of the nonprofit International Scleroderma Network (ISN), which is a 501(c)(3) U.S.-based public charitable foundation, established in 2002. Meet Our Team or Volunteer.
International Scleroderma Network (ISN)
7455 France Ave So #266
Edina, MN 55435-4702 USA
Ask for our Welcoming Email!
Toll Free US/Canada Scleroderma Hotline
*5-13-2015: This is a temporary number while our usual 1-800-564-7099 is being ported to a new provider.