When a person has symptoms of various connective tissue diseases without meeting the full criteria for any one of them, it is often called Undifferentiated Connective Tissue Disease (UCTD). (Also see Difficult Diagnosis)
Undifferentiated Connective Tissue Disease at risk for Systemic Sclerosis (SSc) (so far referred to as very early/early SSc or pre-SSc). This nosographic approach is instrumental to plan future studies devoted to investigate validated biomarkers heralding the development of major vascular disease manifestations as well as skin and/or organ fibrosis in patients at risk. PubMed, Autoimmun Rev, 11/18/2014.
Impaired endothelial function in patients with undifferentiated connective tissue disease (UCTD): a follow-up study. The data suggest that the presence of inflammation and autoantibodies provoke endothelial cell activation and/or injury in UCTD patients. PubMed, Rheumatology (Oxford), 2014 Jun 10.
The diagnosis and classification of undifferentiated connective tissue diseases (UCTD). Criteria for early phases of CTD may offer a valuable guide to the treating physician to set up appropriate follow up schedules as well as therapeutic protocols. PubMed, J Autoimmun, 2014 Feb 8.
SCLERO.ORG is the world leader for trustworthy research, support, education and awareness for scleroderma and related illnesses, such as pulmonary hypertension. We are a service of the nonprofit International Scleroderma Network (ISN), which is a 501(c)(3) U.S.-based public charitable foundation, established in 2002. Meet Our Team or Volunteer.
International Scleroderma Network (ISN)
7455 France Ave So #266
Edina, MN 55435-4702 USA
Ask for our Welcoming Email!
Toll Free US/Canada Scleroderma Hotline
*5-13-2015: This is a temporary number while our usual 1-800-564-7099 is being ported to a new provider.