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Autoimmune Diseases

Anemia of Chronic Disease
Antiphospholipid Syndrome
Ankylosing Spondylitis
Arthritis
Asthma
Autoimmunity
Behcet's
Cancer
Celiac Disease
Chronic Fatigue Syndrome
Depression
Dermatology (General)
Dermatomyositis
Diabetes
Ear Diseases, Autoimmune
Ehlers-Danlos syndromes (EDS)
Endometriosis
Eye Diseases, Autoimmune
Fatigue
Fibromyalgia
Glaucoma/Retinal Involvement
Guillain-Barre
Idiopathic Thromocytopenic Purpura
Interstitial Cystitis
Leukemia
Marfan syndrome (MFS)
MCTD
Multiple Sclerosis
Myasthenia Gravis
Narcolepsy
Neuromuscular Diseases
Pancreatitis, Autoimmune
Pancytopenia
Polyarteritis Nodosa
Polymyositis
Psoriasis, PsA
Rheumatoid Arthritis
Sarcoidosis
Scleroderma
Similar Skin Diseases
Systemic Lupus (SLE)
Systemic Autoimmune Rheumatic Diseases
Thrombotic Purpura (TTP)
Thyroid Disease
TB & Scleroderma
Tuberculous Fasciitis
UCTD
Vasculitis
Vulvodynia
Warts
Wegener's Granulomatosis

Anemia of Chronic Disease

Anemia of Chronic Disease. Anemia refers to a deficiency in the blood. Anemia most commonly refers to insufficient iron resulting in a shortage of hemoglobin, but the term is also used to indicate vitamin deficiency or blood loss. ISN.
Overview: What is Anemia?
What is Anemia of Chronic Disease?
Types of Anemia
Symptoms
Diagnosis
Causes
Treatments
Personal Stories

Antiphospholipid Syndrome

Antiphospholipid Syndrome Symptoms include deep vein thrombosis, chronic leg ulcers, recurrent miscarriages, headache, heart attacks, renal vein and artery thrombosis, pulmonary embolism, and pulmonary hypertension. ISN.
Overview
APS and Heart Disease
Scleroderma and APS
Diagnosis
Symptoms
Complications
Treatments
Causes and Research
Support Resources
Personal Stories

Ankylosing Spondylitis

Ankylosing spondylitis is a type of of inflammatory arthritis that affects areas and joints in the spine. ISN.

Arthritis

Arthritis. Scleroderma is classified as an arthritic disease, along with rheumatoid arthritis, lupus, dermatomyositis, and more than 100 other medical conditions. ISN.
Overview of Arthritis
Autoimmune Arthritis
Juvenile Idiopathic Arthritis
Complications with Arthritis
Diagnosis of Arthrtis
Managing Arthritis

Symptoms of Arthritis
Treatments for Arthritis

Asthma

Asthma is a chronic lung disease where inflammation causes your airways to narrow. ISN
Overview
Autoimmunity
Causes
Treatments
Patient Stories

Autoimmune Ear Disease

Autoimmune Ear Disease Scleroderma can affect every part of the body, including the ears. Many autoimmune diseases can cause Autoimmune Ear Disease. ISN.
What is Autoimmune Ear Disease?
Causes: Scleroderma
Causes: Medications
Ménière's Disease
Tympanosclerosis
A Patient's Perspective
Research
Personal Stories
Related Links

Autoimmunity

Overview
Causes
Diagnosis
Polyautoimmunity
Symptoms
Treatments
Autoimmunity and Other Diseases
Hormone Replacement

Behcet's

Behcet's disease is an autoimmune disease that causes mouth sores, genital sores, inflammation inside of the eye, skin problems, and arthritis. ISN.
What is Behcet's?
Symptoms of Behcet's
Causes of Behcet's
Diagnosis of Behcet's
Treatments for Behcet's

Cancer

Scleroderma and Cancer. Systemic sclerosis (scleroderma) may be associated with an increased incidence of cancer, including breast cancer, B-cell lymphoma, lung cancer and tongue cancer. ISN.
Overview
Angiosarcoma
Autoantibodies
Breast Cancer
Cervical Cancer
Gastrointestinal Tract Cancer
Lymphoma
Malignant Atrophic Papulosis/Degos
MALT Lymphoma
Non-Hodgkin's Lymphoma
Medications and Cancer
Liver Cancer
Lung Cancer
Melanoma
Myeloma (Bone Marrow Cancer)
T Cell Lymphoma
Tongue and Oral Cancer
Tumors
Personal Stories

Celiac Disease and Gluten Sensitivity

Celiac Disease and Gluten Sensitivity. Celiac disease is a known cause of scleroderma and dozens of other autoimmune diseases, including Hashimoto's thyroiditis, psoriasis, and Sjogren's syndrome. ISN.
What is Gluten Sensitivity?
What is Celiac Disease?
Causes
CD and Scleroderma
CD and Autoimmunity
Diagnosis
Diets and Celiac Disease
Symptoms
Treatment
Media Articles
Personal Stories

Chronic Fatigue Syndrome (CFS)

Chronic Fatigue Syndrome Symptoms, diagnostic criteria, treatments and research for CFS and Fibromyalgia. ISN.
What is CFS?
Causes of CFS
Diagnosis of CFS
Treatments of CFS
Related Symptoms or Disorders
–Relationship Between CFS/FMS
–Neurological
–Pain
Disability Info for CFS
Personal Stories about CFS

Depression

Overview
With Autoimmunity
Treatments
Diet
Personal Stories

Dermatology (General)

Dermatology a great site. DermWeb.

Dermatomyositis and Polymyositis

Dermatomyositis and Polymyositis. Polymyositis is an inflammatory condition of the muscles ; dermatomyositis is an inflammatory condition of the skin and muscles, which causes a distinctive rash. ISN.
Myopathy and Myositis
What is Dermatomyositis?
What is Polymyositis?
Symptoms
Diagnosis
Mortality and Prognosis
Treatments
Research
Personal Stories

Diabetes

Diabetes. Topics include symptoms, causes, diagnosis, treatments, research, personal stories and media stories about diabetes. ISN.
Overview of Diabetes
Symptoms and Complications of Diabetes
Causes of Diabetes
Diagnosis of Diabetes
Scleroderma and Diabetes
Prevention of Diabetes
Diabetic Supplies
Treatment for Diabetes
Research on Diabetes
Support for Diabetes
Personal Stories of Diabetes
Media Stories about Diabetes

Ehlers-Danlos syndrome (EDS)

Ehlers-Danlos syndromes and Marfan syndrome. Ehlers-Danlos syndromes (EDS) and Marfan syndrome (MFS) are multisystemic disorders that primarily affect the soft connective tissues. PubMed. Best Practice & Research Clinical Rheumatology Vol 22, Issue 1, March 2008, Pp 165-189. (Also see: Marfan Syndrome)

Endometriosis

Endometriosis Patient Stories
Dawn M: Linear/Systemic Scleroderma My family and I were informed by the doctors, that the localized/linear form of scleroderma that I was diagnosed with, would never progress into the potentially fatal, systemic form...
Krisha S: Multiple Autoimmune Condition I have endometriosis, multiple sclerosis (MS), fibromyalgia, and Stiff Person Syndrome...
Kym: Diffuse, CREST Scleroderma, Lupus and Fibromyalgia It all started with Raynaud's in my fingers and toes when I was about nineteen years old, in 1979...
Nina: Fibromyalgia, Raynaud's, Limited Scleroderma/CREST That is when I found ISN! The volume of reliable, informative, trusted information that I found on this site completely overwhelmed me...
Rachelle: Endometriosis and Interstitial Cystitis I am just happy after two and a half years to know that I have a real answer and I can get better...
Star S: Morphea and Systemic Scleroderma I was diagnosed with morphea at age seven. Now at age thirty-three, I have recently developed systemic scleroderma with gastrointestinal manifestations, Sjogren's syndrome, inflammatory arthritis, malabsorption...

Fibromyalgia and Chronic Fatigue Syndrome

Fibromyalgia and Chronic Fatigue Syndrome Symptoms, diagnostic criteria, treatments and research for CFS and Fibromyalgia. ISN.
Overview
Causes
Diagnosis
Treatments
Complications
Related Disorders
Autoimmune/Scleroderma
Gastrointestinal
Interstitial Cystitis
Lupus
PMS
–RLS
Scleroderma
TMJ
CFS/FMS?
Disability
Research
Psychosocial Research
Medical: Pain
Support
Personal Stories

Guillain-Barre Syndrome

Home Intravenous Immunoglobulin Therapy Safe in Patients With Neuroimmunological Disorders. Intravenous (IV) immunoglobulin therapy has a favourable safety profile for patients with neuroimmunological disorders such as Guillain-Barré Syndrome, chronic inflammatory demyelinating polyneuropathy, myasthaenia gravis, polymyositis, dermatomyositis, and multifocal motor neuropathy. Doctor's Guide Channel. 04/18/08. (Also see: IVIg and Dermatomyositis/Polymyositis)
Do Bacteria or Viruses Cause MS? Though it hasn't been clear as to the cause of this immune system miscue, a new study from Switzerland suggests that a certain bacterium or virus may be the culprit. These bacterial infections, the Swiss study team claims, induce a kind of self-recognition that may contribute to some autoimmune diseases such as MS and Guillain-Barre syndrome (GBS). MS Neighborhood. 07/08/05. (Also see: Multiple Sclerosis)

Idiopathic Thrombocytopenic Purpura

(Case Report) A rare association of localized scleroderma (LS) type morphea, vitiligo, autoimmune hypothyroidism, pneumonitis, autoimmune thrombocytopenic purpura and central nervous system vasculitis. It is likely that localized scleroderma has an autoimmune origin and in this case becomes part of multiple autoimmune syndrome (MAS), which consist of the presence of three or more well-defined autoimmune diseases in a single patient. PubMed, BMC Res Notes. 2012 Dec 20;5:689 (Also see: Causes of Morphea, Vitiligo, Hashimoto's Thyroiditis, Vasculitis, and Multiple Autoimmune Syndrome)
What Is Idiopathic Thrombocytopenic Purpura? Idiopathic thrombocytopenic purpura (ITP) is a bleeding condition in which the blood doesn't clot as it should. This is due to a low number of blood cell fragments called platelets. National Heart Lung and Blood Institute. 2010.
Immune thrombocytopenia purpura. Immune thrombocytopenic purpura (ITP), once known as idiopathic thrombocytopenic purpura, is an autoimmune disorder. Hunt CW. Medsurg Nurs. 2010 Jul-Aug;19(4):237-9.
Perinatal management of immune thrombocytopenic purpura--a case report and review of literature. Immune thrombocytopenic purpura is principally a disease of young women. Therefore it may often be associated with pregnancy. Gupta RS. J Indian Med Assoc. 2010 Jan;108(1):42, 47-8.

Interstitial Cystitis

Interstitial Cystitis (bladder involvement) ISN.
Overview
Autoimmune
Fibromyalgia
Diagnosis
Treatments
Overactive Bladder
Patient Stories

Leukemia

It is rare, but scleroderma has been associated with Large Granular Lymphocyte Leukemia. Medscape.
New Drug May Be Best Treatment for Leukemia Yet. It's called ibrutinib, and it's a potential breakthrough in treating chronic lymphocytic leukemia (CLL) that could leave patients with fewer side effects than chemotherapy. Times Healthland, 06/20/2013.
Dermatomyositis (DM) associated with acute myelocytic leukemia (AML). We present here a case presenting with DM and diagnosed to be suffering from AML on admission. This happens to be the second reported case of DM and AML with no latent period between the two diseases. (PubMed) A. Shrivastav. Rheumatol Int. March 2010. (Also see: Dermatomyositis)

Marfan Syndrome (MFS)

What is Marfan Syndrome? It is a heritable condition that affects the connective tissue. It can affect many body systems, including the skeleton, eyes, heart and blood vessels, nervous system, skin and lungs. National Marfan Foundation.
Ehlers-Danlos syndromes and Marfan syndrome. Ehlers-Danlos syndromes (EDS) and Marfan syndrome (MFS) are multisystemic disorders that primarily affect the soft connective tissues. PubMed. Best Practice & Research Clinical Rheumatology Vol 22, Issue 1, March 2008, Pp 165-189. (Also see: Ehlers-Danlos Syndromes)

Mixed Connective Tissue Disease

Scleroderma in Overlap Scleroderma can occur in overlap with other autoimmune diseases, such as lupus, dermatomyositis or polymyosits, and rheumatoid arthritis. ISN.
Overview of Polyautoimmunity
Scleroderma in Overlap
Connective Tissue Disease (CTD)
Mixed Connective Tissue Disease (MCTD)
Multiple Autoimmune Syndrome
Shared Autoimmunity
Undifferentiated Connective Tissue Disease (UCTD)
Overlap Patient and Caregiver Stories

Multiple Sclerosis

Multiple Sclerosis Topics include symptoms, overlap, treatments, research, support organizations, personal stories and media stories about MS. ISN.
Overview of Multiple Sclerosis
Symptoms of MS
Overlaps with MS
MS and Glandular Fever
MS and Scleroderma
Causes of MS
Treatments and Clinical Trials
MS Research
Personal Stories About MS
Support Organizations
MS Media Stories

Myasthenia Gravis (MG)

Myasthenia gravis is a neuromuscular autoimmune disease that is sometimes associated with scleroderma or other autoimmune diseases. ISN.
What is Myasthenia Gravis?
Symptoms of MG
Pregnancy and MG
Scleroderma and MG
Treatments for MG
Research about MG
Personal Stories about MG

Narcolepsy

Narcolepsy and Sleep. Narcolepsy is a neurological disorder caused by the brain's inability to regulate sleep-wake cycles normally. The main features of narcolepsy are excessive daytime sleepiness and cataplexy. National Sleep Foundation. (Also see: Sleep Disorders)

Neuromuscular Diseases

Neuromuscular diseases that may be associated with scleroderma include polymyositis, dermatomyositis, and inclusion body myositis. (Also see: Overlap Syndrome). ISN.

Pancreatitis, Autoimmune

Autoimmune pancreatitis is a chronic pancreatitis that is usually treated with corticosteroids, and that has recently been found to be more systemic than previously thought in that it can affect organs other than the pancreas. ISN.
Overview of Autoimmune Pancreatitis (AIP)
Autoimmune Pancreatitis and Other Diseases
Causes of AIP
Diagnosing AIP
Treating AIP

Pancytopenia

Pancytopenia is a medical condition in which there is a reduction in the number of red and white blood cells, as well as platelets. Wikipedia.
Methotrexate-induced pancytopenia more common than expected. Virtual Rheumatology Centre, 08/06/05.
A case of Behcet's disease with esophageal ulcers complicated with systemic sclerosis, chronic hepatitis C, and pancytopenia. This is a rare case of Behcet's disease complicated with esophageal ulcers, systemic sclerosis, chronic hepatitis C, and pancytopenia. Of interest is the mechanism of coincidence of these diseases from the pathological point of view. PubMed. Nihon Rinsho Meneki Gakkai Kaishi. 2004 Jun;27(3):164-70. (Also see: Behcet's and Liver Involvement)
A case of scleroderma with pancytopenia due to lack of trace elements. As patients with scleroderma sometimes develop gastrointestinal problems and are needed intravenous nutrition of long duration, they should be paid attention to lack of trace elements that can be a cause of hematologic complications. PubMed. Ryumachi 2002 Dec;42(6):903-9. (Also see: Gastrointestinal Involvement)

Polyarteritis Nodosa (PAN)

Incidence and survival rates in Wegener's granulomatosis (WG), microscopic polyangiitis (MPA), Churg-Strauss syndrome and polyarteritis nodosa. The incidence of WG and MPA was equal in our district, but there was a difference in survival rates related to age and renal function. A progressive increase in age-specific incidence rates was observed. AJ Mohammad. Rheumatology (Oxford). 2009 Dec. (Also see: Wegener's Granulmatosis)
Postirradiation morphea and subcutaneous polyarteritis nodosa: Case report and literature review. Postirradiation morphea is an uncommon condition but is being increasingly recognized. Radiation may be responsible for inducing some of the pathogenic changes seen in scleroderma and other autoimmune diseases. PubMed. Semin Arthritis Rheum. 2005 Apr;34(5):728-34. (Also see: Causes of Morphea and Causes of Scleroderma: Radiation)

Polymyositis

Dermatomyositis and Polymyositis. Polymyositis is very similar to dermatomyositis but without the rash. It causes inflammation and weakness of muscles and is sometimes associated with systemic scleroderma. ISN. (Also see: Types of Scleroderma and Overlap Syndrome)

Psoriasis and Psoriatic Arthritis

Psoriasis Health Center. WebMD.
Overview
Cause
Complications
Diagnosis
Mortality and Prognosis
Treatments

Rheumatoid Arthritis

Rheumatoid Arthritis (RA) is a chronic autoimmune disease that primarily affects the joints. However, it may also cause anemia, eye inflammation, heart attacks, heart failure, myocarditis, pericarditis, pleurisy, vasculitis, shortness of breath, skin ulcers, stomach ulcers, strokes, and neuropathies (numbness and tingling). ISN.
Overview
Symptoms and Complications
Causes
Diagnosis
Antibodies
RA in Overlap
Prevention
Treatments
Support
Personal Stories
Media Stories

Sarcoidosis, Sarcoiditis

Sarcoidosis. Sarcoidosis typically begins in the lungs, however it can affect any part of the body. The first symptom of sarcoidosis is usually shortness of breath. ISN.
Overview
Causes
Diagnosis Symptoms
Treatment
Personal Stories

Systemic Autoimmune Rheumatic Diseases

Systemic Autoimmune Rheumatic Diseases are different from most autoimmune diseases in that they affect many organs, cells or tissues simultaneously rather than just one. Examples of rheumatic diseases are systemic sclerosis (systemic scleroderma), lupus, rheumatoid arthritis, Sjögren's, dermatomyositis, and polymyositis. Examples of non-rheumatic diseases are diabetes, autoimmune hepatitis, autoimmune thyroid disease, and psoriasis. ISN.
Overview
Symptoms and Complications
Causes
Diagnosis
Antibodies
RA in Overlap
Prevention
Treatments
Support
Personal Stories
Media Stories

Systemic Lupus Erythematosus (SLE)

Systemic Lupus Erythematosus (SLE) is an autoimmune disease that can cause a multitude of symptoms. Lupus can occur in overlap with scleroderma and other autoimmune diseases. Scleroderma is also frequently misdiagnosed as lupus in its initial stages. ISN.
Overview
Symptoms
Causes
Diagnosis
Diet/Nutrition
Antibodies
Scleroderma and Lupus
Overlapping Diseases
Pediatric Lupus
Treatments
Research
Support
Personal Stories
Media Stories

Thrombotic Thrombocytopenic Purpura (TTP)

Thrombotic Thrombocytopenic Purpura (TTP) is a blood disorder that causes blood clots to form in small blood vessels around the body, and leads to a low platelet count (thrombocytopenia). Medline Plus.

Thyroid: Hashimoto's Thyroiditis and Graves Disease

Thyroid: Graves' Disease and Hashimoto's Thyroiditis. It is common for people with scleroderma to also have other health problems, such as thyroid disease. The two main types of thyroid disease fall into hyperthyroidism (Grave's disease), and hypothyroidism (Hashimoto's thyroiditis). ISN.
Overview
With Scleroderma
With Other Diseases
Graves' Disease
Hashimoto's
Research
PatientSupport
Personal Stories

Tuberculosis and Scleroderma

What is Tuberculosis? Tuberculosis is a bacterial disease usually affecting the lungs (pulmonary TB). Other parts of the body can also be affected, for example lymph nodes, kidneys, bones, joints, etc. (extrapulmonary TB). New York State Department of Health.
Drug-Resistant TB a ‘Ticking Bomb,’ Warns WHO. The World Health Organization (WHO) warns of a “ticking time bomb” as tuberculosis is getting increasingly resistant to antibiotics. Times Healthland, 12/12/2013.
Associations between selected immune-mediated diseases and tuberculosis (TB): record-linkage studies. These two databases show that patients with some immune-mediated diseases have an increased risk of TB, although we cannot explicitly state the direction of risk or exclude confounding. BMC Medicine 2013, 11:97.

Tuberculous Fasciitis in Scleroderma

(Case Report) Tuberculous fasciitis in scleroderma. We here report a case of tuberculous fasciitis manifest with painful swelling of the midposterior muscles of the right thigh without pulmonary tuberculosis in a patient with scleroderma. PubMed. Clin Rheumatol.

Undifferentiated Connective Tissue Disease

Undifferentiated Connective Tissue Disease (UCTD) ISN.
Overview of Polyautoimmunity
Scleroderma in Overlap
Connective Tissue Disease (CTD)
Mixed Connective Tissue Disease (MCTD)
Multiple Autoimmune Syndrome
Shared Autoimmunity
Undifferentiated Connective Tissue Disease (UCTD)
Overlap Patient and Caregiver Stories

Vasculitis

Vasculitis is an inflammation of blood vessels, which can affect many different parts of the body. Sometimes it occurs along with illnesses like lupus or scleroderma. ISN.
Overview
Symptoms and Complications of Vasculitis
Photos of Vasculitis
Causes of Vasculitis
Diagnosis of Vasculitis
Vasculitis and Rheumatic Diseases
Vasculitis and Scleroderma
Treatments for Vasculitis
Personal Stories about Vasculitis

Vulvodynia

Vulvodynia: Vaginal pain can occur in Scleroderma patients from Sjögren's causing excessive vaginal dryness.

Warts

Warts. People with immune deficiencies are more susceptible to contracting the virus that causes warts. Common warts, genital warts, and plantar warts are all caused by different strains of the human papillomavirus. Warts.org.

Wegener's Granulomatosis

Wegener's Granulomatosis (WG) is a type of vasculitis (inflammation of the blood vessels). ISN.
Overview
Symptoms
Diagnosis
Treatments
Causes
Prognosis
Research
Personal Stories

Footnotes

(1) Medscape requires (free) sign up and password. You do not need to be a medical professional to use Medscape. However this makes for slower access to the site for first-time users.
 
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