| Associated Conditions: MAIN MENU | | | | Autoimmune Diseases: Diabetes |  Hello, I am Janey Willis, ISN Guide to Diabetes. Type 1 Diabetes is an autoimmune disease, and Type 2 Diabetes is caused by risk factors such as lifestyle, ethnicity, age, and pregnancy. The majority of people with diabetes are Type 2. This page has not yet been medically edited. Just because something is listed here does not mean an individual patient will ever experience it. See Disclaimer. | | | |
| Research on Diabetes |
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| Clinical Trials for Diabetes |
| Clinical Trials. American Diabetes Association |
| Opportunities to Participate in Clinical Studies. Type 1 Diabetes Clinical Studies Seeking Volunteers. National Institute of Diabetes & Digestive & Kidney Diseases. |
| Diabetes Prevention Trial--Type 1. Neither low-dose insulin injections in people at high risk for developing type 1 diabetes nor insulin capsules taken orally by people at moderate risk for type 1 diabetes were successful at preventing or delaying diabetes. National Institute of Diabetes & Digestive & Kidney Diseases, 07-01-03. |
| Research on Diabetes |
| Innate immunity and its role in type 1 diabetes. The discovery that innate signaling pathways are involved in the mechanism that may trigger islet inflammation and destruction holds great promise for the identification of new innate signaling molecules that could be targeted to specifically inhibit the autoimmune process to prevent autoimmune diabetes. (PubMed) Zipris, D. Curr Opin Endocrinol Diabetes Obes. August 2008. |
| Triggering the autoimmune response against islets in type 1 diabetes. The authors found that transplanted islet cells, but not bone marrow cells, expressing native B16:Y insulin (tyrosine at position 16 of insulin B chain) restored anti-insulin autoimmunity in mice that lacked native insulin genes. SpiritIndia.com. July 2007. (Also see: Causes of Scleroderma: B and T cells ) |
| Immunization Against Type 1 Diabetes - Mice Successfully Treated. Researchers in Toulouse (France) and Berlin-Buch have successfully treated type 1 diabetic mice with a vaccination. The researchers showed that, in principle, it is possible to treat autoimmune diseases by inducing "active tolerance". That means activating the immune system so that it no longer attacks the body's own structures, but instead protects them from the immune attack. Medical News Today. 05/24/07. (Also see:Causes of Scleroderma: B and T cells ) |
| Joslin-led study uncovers role of appetite hormone MCH in insulin production. Findings may lead to treatments that stimulate insulin production. A new Joslin Diabetes Center-led study has shown conclusively that a neuropeptide, melanin concentrating hormone (MCH), found in the brain and known for its role in increasing appetite in people, plays a role in the growth of insulin-producing beta cells and the secretion of insulin. EurekAlert! 01/25/07. |
| Natural compounds block autoimmune response in diabetes, arthritis. Natural compounds from a sea anemone extract and from the rue shrub plant block autoimmune disease responses in both type 1 diabetes and rheumatoid arthritis, U.S. researchers report. EurekAlert! University of California, Irvine. 11/06/06. (Also see: Causes of Scleroderma: B Cells and T Cells and Rheumatoid Arthritis ) |
| Researchers discover possible cure for Type 1 Diabetes. Dr. Jerry Nadler, along with other researchers, discovered a way to mix medications that would reverse Type 1 diabetes in mice, for good. WCAV. 04/18/06. |
| Researchers reverse juvenile diabetes in animal model. Subcutaneous injection of dendritic cells into the abdominal/pelvic area near the pancreas and lymph nodes, blocks the T cells as they travel to the pancreas to destroy beta cells. The injections interrupted the T cell and beta cell interaction, allowing the beta cells in the pancreas to regenerate. This enabled the pancreas of the mice to begin producing insulin again. RXPG News 03/28/06. |
| Islet Cell Replacement Initiative Researchers. These research awards support investigators who are developing basic science, clinical and translational research focusing on islet (insulin-producing) cell replacement in type 1 diabetes. The work of these researchers could lead to procedures that would ultimately restore the body's ability to produce insulin. American Diabetes Association. |
| Researchers Studying Diabetes Find a Possible Cause of Infertility. scientists at the National Institutes of Health and colleagues report that in the course of animal studies to understand diabetes, they may have uncovered a previously unknown cause of infertility in women. National Institutes of Health. 02/01/06. |
| Rec department offers yoga for everyone. Yoga promotes relaxation, improves circulation, and reduces stress and anxiety. Many diseases and conditions have been linked to overactive stress responses including: cardiovascular disease, depression, anxiety, obsessive-compulsive disorder, some types of diabetes mellitus, some autoimmune diseases, colitis, irritable bowel syndrome, reproductive problems, and suppression of the immune system. Pulitzer Central Coast Newspapers 05/12/05. |
| 'Eat what you want' pill caution. Experts advise caution about claims of a pill that could enable people with diabetes and coeliac disease to eat foods that are normally off-limits. Researchers at the University of Baltimore say a pill that makes the gut more watertight could allow these patients to eat whatever they want. BBC News. 03/07/05. |
| Should my age or health condition influence my decision to become an organ donor? No. While medical history and age are factors, most people can donate. People with diabetes, hepatitis, and cancer sometimes can donate their organs. The only individuals who cannot donate are those who test positive for the HIV virus. HealthFirst, Florida. (Also see: Postmortem Resources: Organ Donation) |
