| Associated
Conditions: MAIN MENU |
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Autoimmune
Diseases:
Systemic Lupus Erythematosus (SLE) |
| This page was written
by Shelley Ensz, and has
not yet been medically edited. See Disclaimer. |
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| What is Systemic Lupus
Erythematosus (SLE)? |
| Systemic Lupus Erythematosus (SLE)
is an autoimmune disease that can cause a multitude of symptoms.
Lupus can occur in overlap with scleroderma and other autoimmune
diseases. Scleroderma is also frequently misdiagnosed as lupus
in its initial stages. (Also see: Autoimmune
Diseases, Difficult
Diagnosis, What
is Scleroderma?, and Overlap
Syndrome) |
| Lupus
Links. Mick Breske. |
| Systemic
Lupus Erythematosus (SLE/LUPUS). MedicineNet. |
| Types
of Lupus. The various types of lupus include Cutaneous
Lupus, Systemic Lupus (SLE), Drug- Induced Lupus; Overlap
Syndrome; and Neonatal Lupus (rare). Lupus Foundation
of America (Also see: Overlap
Syndrome) |
| Symptoms of Lupus
and Complications |
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| Causes of Lupus |
| Causes
of Lupus. ISN. |
| Diagnosis of Lupus |
| Diagnosis
of Lupus. ISN. |
| Antibodies in Lupus |
| Antibodies
in Lupus. There are over 100 antibodies associated
with lupus. ISN. |
| Scleroderma and Lupus |
| Overlap
Syndrome: When lupus appears along with other autoimmune
diseases such as scleroderma and polymyositis,
it is called Overlap Syndrome. ISN. |
| Sclerodermiform linear lupus erythematosus: A distinct entity or coexistence of two autoimmune diseases? A Case Report. The coexistence of features of chronic cutaneous lupus erythematosus and scleroderma in the same skin lesions is very infrequent and has only been reported in 3 patients. (ScienceDirect) Journal of the American Academy of Dermatology Vol 58, Issue 4, April 2008, Pp 665-667. (Also see: Overlap) |
| Systemic Sclerosis and Systemic Lupus Erythematosus have Distinct Gene Expression Profiles in the Peripheral Blood Cells. These data show that a limited number of genes reliably distinguished SSc from SLE. Shervin Assassi. 38/38. ACR 2007. (Also see: Scleroderma in Overlap) |
| Sclerodermic
linear lupus panniculitis: report of two cases. Lupus
erythematosus panniculitis is a rare disease characterized
by deep subcutaneous nodules, most commonly localized on
the upper limbs and face. We present here the clinical characteristics,
course and laboratory findings of 2 patients having linear
lupus erythematosus panniculitis with localized scleroderma-like
changes. PubMed. Dermatology. 2005;210(4):329-32. (Also
see: Linear
Scleroderma, and Overlap
Syndrome) |
| Prevention of Lupus |
| Can
Broccoli Prevent Lupus? Animal Studies Suggest It Can,
but Human Trials Are Needed. A compound found in abundance
in cruciferous vegetables, known as indole-3-carbinol (I3C),
delayed the onset of lupus and reduced its severity in mice
genetically bred to develop the disease. WebMD. 11/06/03. |
| Treatments for Lupus |
| Treatments
for Lupus. ISN. |
| Lupus Research |
| Vitamin D deficiency in systemic lupus erythmatosus(SLE): prevalence, predictors and clinical consequences. Vitamin D insufficiency and deficiency are common in patients with SLE and are associated with sun avoidance. G. Ruiz-Irastorza. Rheumatology Advance Access. April 14, 2008. |
| Medical researchers predict 'flood of discoveries' soon. What allows Harley and researchers worldwide to come closer to targeting lupus' underpinnings is the Oklahoma Medical Research Foundation's Lupus Family Registry and Repository, a decade-long, $20 million collaboration with the National Institutes of Health. It contains genetic profiles and blood samples from thousands of lupus sufferers and their relatives. NewsOK.com. 09/14/07. |
| New
Insights Into Autoimmunity And Depression. Some studies
have described a possible link between Lupus's most severe
psychiatric manifestation, psychosis, and a protein autoantibody
associated with the central nervous system, anti-ribosomal
P. ScienceDaily. 03/09/07. (Also see: Emotional
Adjustment) |
| The
Effect of Menopause on Disease Activity in Systemic Lupus
Erythematosus. Although premenopausal women with SLE
have more disease activity than postmenopausal women with
SLE, there is a constant rate of improvement over time. This
improvement is not due to change in menopausal status. Journal
of Rheumatology. Vol 33: NO 11:2192 NOV 2006. |
| A
statistical analysis of the interrelationships between disease
activity in different systems in systemic lupus erythematosus
(SLE). Four hundred and forty patients with SLE were
followed for a period of 10 yr. Previous disease history
and involvement of other systems determine a patient's chance
of developing further episodes of active disease in SLE. Rheumatology
2006 45(3):308-313. |
| Effects
of Vitamins C and E on Oxidative Stress Markers and Endothelial
Function in Patients with Systemic Lupus Erythematosus: A
Double Blind, Placebo Controlled Pilot Study. Combined
administration of vitamins C and E was associated with decreased
lipid peroxidation, but did not affect endothelial function
in patients with SLE after 3 months of therapy. J. Rheumatol
No. 2 February 2005;32:275-82. |
| Despite
causes of lupus proving complex, critical 'checkpoint' suggesting
new therapy is revealed. Scientists at The Rockefeller
University have determined that the autoimmune disease lupus
results from a combination of genetics that likely varies
from person to person, and that a common "gatekeeper" gene
called FCRgIIB is critical to the prevention of this devastating
disease. EurekAlert! 01/27/05. |
| Lupus
Research Institute (LRI) Reports Unprecedented Success in
First Round of Grants. Through its Novel Research Program,
the LRI supports investigators nationwide in their pursuit
of new approaches to improve treatment, prevent and cure
lupus. Immune Tolerance Network, Jan 20, 2004. |
| Support for Lupus |
| Lupus
Foundation of America launches new national magazine The
Lupus Foundation of America has a magazine dedicated
to lupus, a life-threatening autoimmune disease affecting
1.5 million Americans. Lupus Foundation of America. |
| Personal Stories About
Lupus |
| Lupus
Personal Stories. These stories include suspected lupus
and lupus misdiagnosis, as well as those with Overlap Syndrome. (Also
see: Difficult
Diagnosis and Overlap
Syndrome) |
| Aileen:
CREST Scleroderma Oh, the wonderful feeling to have
a doctor sit there and tell you that you are not imagining
things... |
| Amy
B: Limited Scleroderma with CREST I am a full time
pharmacist in a pediatric hospital. In February or March
of this year, I began to be very intolerable of the cold... |
| Anna:
Linear Scleroderma (Poland) I realised that it is
not worthwhile to give up, even during the most difficult
moments; it is necessary to fight and to believe that it
will be better. If I had not believed I would not have been
alive now... |
| (Italiano)
Antea: Sindrome di Sjogren e il Lupus Eritematoso Sistemico Sono
Angela dalla provincia di pesaro, ho 29 anni e da ieri ho
scoperto di avere la Sindrome di Sjogren... |
| Many
More Personal Stories about Lupus. ISN. |
| Lupus Media Stories |
| Media
Stories about Lupus. ISN. |
