There are a wide variety of autoantibodies associated with lupus. Some of the antibodies are helpful in diagnosing the illness, while others are more useful in detecting disease activity or potential complications. (Also see: Autoimmune Diseases and Overview of Lupus)
Do we need new autoantibodies in lupus (SLE)? Some autoantibodies are useful for diagnosis of SLE. Others are clinically important because of associations with a particular manifestation of SLE. Scofield RH. (PubMed) Arthritis Res Ther. 2010 May 28;12(3):120.
C Reactive Protein (Anti-CRP)
Anti-CRP antibodies in systemic lupus erythematosus. Anti-CRP autoantibodies, which are found in 35 to 40% of SLE patients, increase the cardiovascular risk by interacting with the monomeric (degraded) form of CRP. Meyer O. (PubMed) Joint Bone Spine. 2010 Jun 1.
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