Over 2,200+ pages in 22 languages!
 
Skin Diseases Similar to Scleroderma (Main Menu)
Skin Diseases (Main Page)
About Dermatology
Acrokeratoelastoidosis
Atrophoderma Pierini/Pasini
Bullous Pemphigoid
CREST Syndrome
Dermatitis Artefacta
Diffuse Scleroderma
En Coup de Sabre
Eosinophilia Myalgia (EMS)
Eosinophilic Fasciitis
Graft-Versus-Host-Disease
Grzybowski Syndrome
Keloidal Scleroderma
Lichen Sclerosus
Linear Scleroderma
Limited Systemic Scleroderma
Lipodermatosclerosis
Lipodystrophy, Lipoatrophy
Morphea
Myeloma (Bone Cancer)
Nephrogenic Fibrosing Derm
Overlap/UCTD/MCTD
Parry-Rombergs Syndrome
Pemphigus Vulgaris
POEMS
Porphyria Cutanea Tarda
Progeria
Pseudoscleroderma
Radiation Port Scleroderma
Schnitzler Syndrome
Scleredema Adultorum Buschke
Scleroderma
Scleroderma-Like
Scleromyxedema
Stiff Skin Syndrome
Vitiligo
Werner's Syndrome
Scleromyxedema, Lichen Myxedematosus or Papular Mucinosis
This page was written by Shelley Ensz and has not yet been medically edited. See disclaimer.
What is Scleromyxedema?
Causes of Scleromyxedema
Treatments for Scleromyxedema
Scleromyxedema Support
Scleromyxedma Personal Stories
References
What is Scleromyxedema?
Scleromyxedema is a scleroderma-like condition. However, it causes thickening and hardening that makes the skin look too ample, rather than too tight, as in scleroderma. It is also referred to as Scleromyxedema of Groton, lichen myxedematosus, and papular mucinosis. (2)
Scleromyxoedema (Scmyx) Showing the Clinical Picture of Diffuse Cutaneous Systemic Sclerosis. Scmyx and dcSSc are two distinct clinical entities. In our patient, Scmyx was associated with paraprotein production as well as Raynaud's syndrome, polyarthritis, diffuse scleroderma and teleangiectasias, which are not included in Scmyx, but rather resemble dcSSc. Z. Szekanecz. AB0292 EULAR 2006.
Causes of Scleromyxedema
Scleromyxoedema-like changes in four renal dialysis patients. We describe four renal dialysis patients from our hospital who, over a 6-month period, developed erythematous, thickened, indurated dermal plaques. The plaques were limited to the limbs and in three patients there were associated flexion contractures. The clinical features most resembled scleromyxoedema. We believe this to be a new and distinct phenomenon. PubMed. Br J Dermatol 2003 Mar;148(3):563-8 (Also see Renal Involvement)
Treatments for Scleromyxedema
Scleromyxedema Mimicking Systemic Sclerosis Treated with Thalidomide. Thalidomide dramatically and promptly improved the skin manifestations, suggesting that this drug may be considered as an alternative treatment of patients with scleromyxedema. E. Guevara-Gutierrez. AB0293 EULAR 2006.
IVIG and Thalidomide Combination is an Effective Novel Therapy for Scleromyxedema. In the majority (83.2%) of cases, an abnormal paraproteinemia is present. IVIG and thalidomide combination is an effective novel treatment of scleromyxedema with systemic involvement and associated light chain monoclonal gammopathy. Petros Efthimiou. ACR Conference Oct. 2003.
Scleromyxedema Support
Scleromyxedema Survivors. This patient site offers online support, patient stories, and information about Scleromyxedema. Phyllis K. Phillips, Scleromyxedema Survivors.
Scleromyxedema Online Support Group. If you or a family member suffer from Scleromyxedema please join this this group and maybe together we will all learn to understand this disease. Scleromyxedema Support Group.
Scleromyxedema Personal Stories
Phyllis K. Phillips: Scleromyxedema I have created a website, Scleromyxedema.com, to share my experience with others living with this scleroderma-like disease and to provide a forum/network of support...
References
(2) Scleromyxedema information from the book Systemic Sclerosis, First Edition by Dr. Phil Clements and Dr. Daniel Furst, pages 100-102.
Keep on Surfing!
Go to Diseases Similar to Scleroderma: Vitiligo
Contact ISN. We are a full-service nonprofit agency.
Email: isn@sclero.org or
Post in Sclero Forums!
International Scleroderma Network (ISN)
7455 France Ave So #266
Edina, MN 55435-4702
USA
Toll Free Hotline in U.S.
1-800-564-7099
Direct Line
1-952-831-3091 (U.S.)
(We are also known as the Scleroderma from A to Z web site.)
© Copyright 1998-2008 International Scleroderma Network
All Rights Reserved