| Skin Diseases Similar to Scleroderma (Main Menu) |
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| Scleromyxedema, Lichen Myxedematosus or Papular Mucinosis |
| This page was written by Shelley Ensz and has not yet been medically edited. See disclaimer. |
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| What is Scleromyxedema? |
| Scleromyxedema is a scleroderma-like condition. However, it causes thickening and hardening that makes the skin look too ample, rather than too tight, as in scleroderma. It is also referred to as Scleromyxedema of Groton, lichen myxedematosus, and papular mucinosis. (2) |
| Scleromyxoedema (Scmyx) Showing the Clinical Picture of Diffuse Cutaneous Systemic Sclerosis. Scmyx and dcSSc are two distinct clinical entities. In our patient, Scmyx was associated with paraprotein production as well as Raynaud's syndrome, polyarthritis, diffuse scleroderma and teleangiectasias, which are not included in Scmyx, but rather resemble dcSSc. Z. Szekanecz. AB0292 EULAR 2006. |
| Causes of Scleromyxedema |
| Scleromyxoedema-like changes in four renal dialysis patients. We describe four renal dialysis patients from our hospital who, over a 6-month period, developed erythematous, thickened, indurated dermal plaques. The plaques were limited to the limbs and in three patients there were associated flexion contractures. The clinical features most resembled scleromyxoedema. We believe this to be a new and distinct phenomenon. PubMed. Br J Dermatol 2003 Mar;148(3):563-8 (Also see Renal Involvement) |
| Treatments for Scleromyxedema |
| Scleromyxedema Mimicking Systemic Sclerosis Treated with Thalidomide. Thalidomide dramatically and promptly improved the skin manifestations, suggesting that this drug may be considered as an alternative treatment of patients with scleromyxedema. E. Guevara-Gutierrez. AB0293 EULAR 2006. |
| IVIG and Thalidomide Combination is an Effective Novel Therapy for Scleromyxedema. In the majority (83.2%) of cases, an abnormal paraproteinemia is present. IVIG and thalidomide combination is an effective novel treatment of scleromyxedema with systemic involvement and associated light chain monoclonal gammopathy. Petros Efthimiou. ACR Conference Oct. 2003. |
| Scleromyxedema Support |
| Scleromyxedema Survivors. This patient site offers online support, patient stories, and information about Scleromyxedema. Phyllis K. Phillips, Scleromyxedema Survivors. |
| Scleromyxedema Online Support Group. If you or a family member suffer from Scleromyxedema please join this this group and maybe together we will all learn to understand this disease. Scleromyxedema Support Group. |
| Scleromyxedema Personal Stories |
| Phyllis K. Phillips: Scleromyxedema I have created a website, Scleromyxedema.com, to share my experience with others living with this scleroderma-like disease and to provide a forum/network of support... |
| References |
| (2) Scleromyxedema information from the book Systemic Sclerosis, First Edition by Dr. Phil Clements and Dr. Daniel Furst, pages 100-102. |
