| Cardiac (Heart) Involvement (Main Menu) |
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| Cardiac (Heart) Involvement in Systemic Sclerosis (Scleroderma) |
| This page was written by Shelley Ensz, and has not yet been medically edited. See Disclaimer. |
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| Cardiac (Heart) Involvement Overview |
| The Heart in Scleroderma. The heart is one of the major organs involved in scleroderma, the involvement of which can be manifested by myocardial disease, conduction system abnormalities, arrhythmias, or pericardial disease. (Science Direct) Rheumatic Disease Clinics of North America Volume 34, Issue 1, February 2008, Pages 181-190. |
| Cardiac abnormalities common in systemic sclerosis. Left and right heart diseases, including pulmonary arterial hypertension (PAH), left ventricular hypertrophy, and diastolic dysfunction, are frequently found in patients with systemic sclerosis. The Job Cure. (Reuters) 01/01/08. |
| Cardiac Involvement in Systemic Sclerosis: The Strongest Predictive Factor of Prognosis in Patients with Scleroderma. The results disclosed that most frequent cardiac manifestation at the initial evaluation of scleroderma is subclinical arrhythmia. More importantly, cardiac involvement at early stage of the disease is the strongest predictive factor for death. Sumiaki Tanaka. 13/13. ACR 2007. (Also see: Mortality and Prognosis) |
| Cardiac involvement in systemic inflammatory diseases. Modern sophisticated imaging techniques reveal cardiac abnormalities in most of these diseases and the reported frequency of cardiac involvement ranges widely depending upon the applied diagnostic methods and selection of patients. European Heart Journal. Vol 28, No 15 Pp. 1797-1804. (Also see: Autoimmunity) |
| Organ Involvement-Induced Disability In Systemic Sclerosis (SSc) . SSc-related disability is clinically significant and is mostly related to joint, cutaneous and cardio-pulmonary involvement, as well as to the disease-induced fatigue. C. Mihai. AB0514 EULAR 2007. (Also see: Skeletal, Skin, and Pulmonary Involvement) |
| Cardiac (Heart) Symptoms |
| Cardiac (Heart) Symptoms. Common symptoms of heart failure include breathing difficulties, fatigue and exercise intolerance, and coughing. ISN. |
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| Correlation Between Cardiac and Other Diseases |
| The prevalence of coronary artery disease (CAD) in end-stage pulmonary disease: Is pulmonary fibrosis a risk factor? There is significantly more CAD in lung-transplantation candidates with lung fibrosis as compared to those with emphysema, despite the fact that smoking was much more prevalent in the emphysema patients. These results suggest that the inflammatory process in lung fibrosis may involve the coronary arteries as a part of a systemic inflammation rather than an idiopathic fibrotic disease confined to the lungs. G. Izbicki. Respiratory Medicine Volume 103, Issue 9, Pages 1346-1349. (September 2009) (Also see: Pulmonary Fibrosis and Cardiac Involvement) |
| Cardiac involvement in systemic inflammatory diseases (SIDs). Modern sophisticated imaging techniques reveal cardiac abnormalities in most of these diseases and the reported frequency of cardiac involvement ranges widely depending upon the applied diagnostic methods and selection of patients. Better knowledge and awareness of cardiac involvement in SIDs is necessary because it conveys a major risk for increased morbidity and mortality in several of these rare diseases. This has clearly been shown for temporal arteritis, Churg–Strauss syndrome, sarcoidosis, SSc, relapsing polychondritis and others. Daniel C. Knockaert. European Heart Journal 2007 28(15):1797-1804. |
| Antiphospholipid Syndrome (APS) and Heart Disease. ISN. |
| The Association Between Idiopathic Pulmonary Fibrosis and Vascular Disease. People with idiopathic pulmonary fibrosis have an increased risk of vascular disease in comparison to the general population. Richard B Hubbard. Am. J. Respir. Crit. Care Med. August 28, 2008. (Also see: Pulmonary Fibrosis) |
| Discrepancy Between Simultaneous Digital Skin Microvascular and Brachial Artery Macrovascular Post-Occlusive Hyperemia in Systemic Sclerosis (SSc) . Microvascular function is impaired in SSc, whereas brachial artery endothelial function is normal. M. Roustit. J Rheumatol 2008; 35:1576–83. (Also see: Raynaud's) |
| Systemic Scleroderma Heart Involvement |
| Systemic Scleroderma Cardiac (Heart) Involvement. The systemic forms of scleroderma can cause cardiac (heart) problems. One of the earliest symptoms reported by diffuse systemic scleroderma patients is heart irregularities. ISN. |
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| Vascular Disease and Systemic Scleroderma. The vascular system is our circulatory system. It consists of all the vessels that carry blood and lymph through the body, to and from organs. Vessels include arteries, veins, and capillaries. Any condition that affects the vascular system, all of in part, is considered a vascular disease. ISN. |
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| Complications with Systemic Scleroderma Heart Involvement |
| Complications with Systemic Scleroderma Cardiac (Heart) Involvement include atrioventricular heart block, cardiogenic shock, myocardial infarction, and skeletal myopathy. ISN. |
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| Diagnosis of Systemic Scleroderma Cardiac (Heart) Involvement |
| Diagnosis of Systemic Scleroderma Cardiac (Heart) Involvement. It is common for patients with systemic scleroderma to develop heart involvement even without any overt cardiac symptoms, so mandatory assessment of systemic scleroderma heart involvement requires a thorough baseline screening and follow-up monitoring. Diagnostic tests for scleroderma heart involvement may include electrocardiograms (ECG or EKG), echocardiography (ECHO), Holter monitoring, CT scans, and MRI's. ISN. |
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| Treatments for Systemic Scleroderma Heart Involvement |
| Treatments for Systemic Scleroderma Cardiac (Heart) Involvement include Bosentan, and calcium channel blockers such as nicardipine (Cardene) and nifedipine (Adalat, Procardia). ISN. |
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| Research about Systemic Scleroderma Heart Involvement |
| Research about Systemic Scleroderma Heart Involvement. Topics include antibodies, autoimmunity, case studies, and causes of scleroderma heart involvement. ISN. |
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| Patient & Caregiver Stories: Cardiac (Heart) Involvement |
| Patient and Caregiver Stories: Cardiac (Heart) Involvement. ISN. |
| Anastasia: Surviving Granddaughter of a Diffuse Scleroderma Patient Traveling to a different hospital finally we heard scleroderma... |
| Angela S: Overlap Syndrome I am twenty-five years old and I was diagnosed with polymyositis and scleroderma, rheumatoid arthritis, mitral valve prolapse, a heart murmur, and pericarditis... |
| Angiola: Progressive Systemic Scleroderma (Italy) I would very much like to find other people that find themselves in a similar situation... |
| Read more stories... |
| Related Books |
| Mayo Clinic on High Blood Pressure. Sheldon, Md Shep (Editor), Sheldon G. Sheps, Mayo Clinic, Rochester, MN. A family medical book with daily menus, diet, six-step fitness plan, managing medications, issues for women, home monitoring, and more. |
