Severe cases of systemic scleroderma and Raynaud's (as well as other illnesses) may cause a total lack of blood supply to the extremities. When this happens, necrosis (death of tissue) and gangrene may set in, sometimes making it necessary to have the affected part(s) amputated.
Gangrene sets in more frequently among scleroderma patients who smoke or use caffeine, because such substances further constrict blood vessels.
SCLERO.ORG is the world leader for trustworthy research, support, education and awareness for scleroderma and related illnesses, such as pulmonary hypertension. We are a service of the nonprofit International Scleroderma Network (ISN), which is a 501(c)(3) U.S.-based public charitable foundation, established in 2002. Meet Our Team or Volunteer.
International Scleroderma Network (ISN)
7455 France Ave So #266
Edina, MN 55435-4702 USA
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Toll Free US/Canada Scleroderma Hotline
*5-13-2015: This is a temporary number while our usual 1-800-564-7099 is being ported to a new provider.