| LUNG (PULMONARY): MAIN MENU |
| |
| Pulmonary Hypertension: MAIN MENU |
| |
| Treatments for Pulmonary Hypertension |
| |
| Overview |
| Treatments for pulmonary hypertension (PH) include bosentan (Tracleer), endothelin receptors (Sitaxsentan, Ambrisentan), lung transplants, oxygen therapy, sildenafil citrate (Revatio, Viagra), endothelin receptors (Sitaxsentan, Ambrisentan), stem cell transplants, and warfarin (Coumadin). |
| What can be done to treat Pulmonary Arterial Hypertension? Treatment options fall into two main areas: general therapies that are used to reduce symptoms but which do not have a positive impact on the disease progression, and disease-targeted therapies that have been specifically researched in the area of Pulmonary Arterial Hypertension (PAH). Actelion Pharmaceuticals. |
| Medical Therapy for Pulmonary Arterial Hypertension (PAH). This update provides evidence-based treatment recommendations for physicians involved in the care of patients with PAH. Due to the complexity of the diagnostic evaluation required and the treatment options available, referral of patients with PAH to a specialized center continues to be strongly recommended. Chest. 2007; 131:1917-1928. |
| Pulmonary arterial hypertension and systemic sclerosis. Pulmonary arterial hypertension is a serious complication of systemic sclerosis and a leading cause of death in patients with it. Recent publications suggest that a prevalence of 10-15% is likely. PubMed. Presse Med. 2006 Dec;35(12 Pt 2):1929-37. |
| Pulmonary arterial hypertension in collagen disease: findings of the German Network for Systemic Scleroderma (DNSS). The DNSS recommends annual echocardiography for patients with scleroderma and right-heart catheterization if the systolic pulmonary arterial pressure is higher than 35 mmHg. Aggressive immunosuppressive treatment - in the first instance with cyclophosphamide - should be given only if there is also progressive fibrosis. PubMed. Dtsch Med Wochenschr. 2006 Dec;131 Suppl 9:S325-7. |
| A case of systemic scleroderma complicating pulmonary hypertension. This case was treated from an early stage with steroid pulse therapy and CY pulse therapy, accompanied with oral administration of a PGI2 preparation for the pulmonary hypertension. The dermal symptoms improved, and it was possible to maintain a state of remission. PubMed. Nihon Rinsho Meneki Gakkai Kaishi. 2006 Dec;29(6):378-83. (Also see: Juvenile Scleroderma ) |
| Pulmonary hypertension gets a closer look. Researchers have found that excesses or deficiencies of certain substances within the pulmonary artery are linked to a progression of the disease, and several medications have been developed to address those problems. Pittsburgh Post-Gazette. 10/11/06. |
| Successful Treatment of Pulmonary Arterial Hypertension (PH) Associated with Mixed Connective Tissue Disease (MCTD) by Methylprednisolone Pulse Therapy. Our findings suggest the long-term efficacy of methylprednisolone pulse therapy for early PH associated with MCTD. Doppler echocardiography is also very useful to detect early PH in MCTD. S. Ohshima. AB0283 EULAR 2006. (Also see: MCTD) |
| Warfarin (Coumadin) |
| Anticoagulation in pulmonary arterial hypertension: a qualitative systematic review. Seven observational studies evaluating the effectiveness of warfarin comprising 488 patients were identified. Five studies support the effectiveness of anticoagulation therapy, whereas two do not. Eur Respir J 2006; 28:999-1004. |
