Severity and Prognosis for Scleroderma Pulmonary Involvement
The primary cause of scleroderma-related death today is lung involvement; it used to be kidney failure, but that risk has been reduced thanks to dialysis and other treatments.
Connective Tissue Disease-Associated Interstitial Lung Disease (CTD): A Focused Review. The prognosis of patients with CTD having respiratory failure is often quite poor, highlighting the need for prompt and thorough clinical assessments to determine the underlying etiology and implementation of appropriate therapeutic strategies. PubMed, J Intensive Care Med, 2013 Dec 25. (Also see Connective Tissue Disease)
Computed tomography aids scleroderma lung disease prognosis. However, the team suggests that pulmonary function tests (PFTs) may be more practical than HRCT in the clinic. NewsMedical. 10/22/12.
Survival in progressive systemic sclerosis with pulmonary involvement: a single-center experience in Istanbul, Turkey. The objective of the current study was to determine survival and factors that affect survival in progressive systemic sclerosis (SSc) with pulmonary involvement. Zuhur F. Rheumatol Int, 2011 Mar 5.
Prognosis of Pulmonary Hypertension in Systemic Sclerosis (Scleroderma). Early diagnosis and treatment substantially improves the prognosis for pulmonary hypertension associated with systemic sclerosis (scleroderma). ISN.
Predictors of Morbidity and Mortality
Interstitial Lung Disease (ILD) in Undifferentiated Forms of Connective Tissue Disease(CTD). There is much uncertainty and controversy surrounding the suggestive forms of CTD-associated ILD (CTD-ILD) and prospective studies are needed to provide a better understanding of the natural history of these cohorts. PubMed, Arthritis Care Res, 2014 Jul 21.
Prediction of pulmonary complications and long term survival in systemic sclerosis (SSc). This study provides data on long-term outcome of SSc and the timing and frequency of major organ complications. PubMed, Arthritis Rheumatol, 03/03/2014. (Also see Prognosis of Pulmonary Hypertension)
I'm confused! What exactly is the difference between morbidity and mortality?
Morbidity is another term for illness. A person can have several co-morbidities simultaneously. So, morbidities can range from Alzheimer's disease to cancer to traumatic brain injury. Morbidities are NOT deaths. Prevalence is a measure often used to determine the level of morbidity in a population. New York State Department of Health.
Mortality is another term for death. A mortality rate is the number of deaths due to a disease divided by the total population. If there are 25 lung cancer deaths in one year in a population of 30,000, then the mortality rate for that population is 83 per 100,000. New York State Department of Health.
So, morbidity just sounds deadly, but mortality really is.
QOL with Scleroderma
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