Sjögren's Syndrome
This page was written by Shelley Ensz, and has not yet been medically edited. Scleroderma (SD) affects everyone differently. See Disclaimer.
What is Sjögren's?
Symptoms of Sjogren's
Diagnosis of Sjogren's
Similar & Overlaps
Treatments for Sjögren's
Overview of Treatments
Treatments for Dry Eyes
Treatments for Dry Mouth
Sjogren's Research
Overview of Research
Antibodies
Brain Involvement
Causes
Dry Eyes
Online Support
Personal Stories
Media Stories
Symptoms of Sjogren's Syndrome
Symptoms of Sjogren's: Overview
Symptoms: Dry Eyes
Symptoms: Dry Mouth
Symptoms: Dry Vagina
Symptoms: Fatigue
Symptoms: Nervous System
Symptoms: Newborn Heart Problems
Sjogren's and Pregnancy
Symptoms of Sjogren's Syndrome: Overview
Hallmark symptoms of Sjögren's include dry eyes, dry mouth, dry vagina. Sjögren's can also cause fatigue, and it can affect the skin, lungs, heart, kidneys, muscles, and central nervous system. People can also have any of the above symptoms separately, or due to other conditions.
Study documents incidence of and risk factors for dry eye in older persons. Dry eye syndrome is a common source of discomfort among the elderly population, has been associated with rheumatoid arthritis and other autoimmune diseases, and can affect quality of life. Some drugs (e.g., diuretics and antihistamines) are associated with a greater risk, whereas others (angiotensin-converting enzyme inhibitors) are associated with lower risk. EurekAlert! JAMA. 03/08/04.
Characteristics of Scleroderma Patients with Secondary Sjogren's Syndrome (sSS) and Sjogren's Syndrome (pSS) Overlapping Systemic Sclerosis (SSc). We suggest that SSc patients with pSS or sSS are at higher risk to have lung and esophageal involvement especially in presence of diffuse skin involvement. G. Peluso. SAT0224 EULAR 2006.
Symptoms of Sjogren's Syndrome: Dry Eyes
Eye Problems Pain, redness and loss of vision are important problems that require medical attention. Eye problems can warn us of other health problems as well. familydoctor.org
Tear Production. Tears are the watery substance that bathes the eye. They form a film that keeps the cornea moist, protects the eye against infection and helps eye wounds heal. A condition called Sjogren's Syndrome affects the fluid-producing glands in the body and leads to dry eye symptoms. WSOCTV.com 06/01/06.
Prevalence and risk factors of dry eye syndrome. Systemic diseases were diagnosed in 36% of female cases with dry eye syndrome, including 22.3% rheumatoid arthritis and 9.8% Sjogren syndrome. 46.6% of male patients had systemic diseases: 32% rheumatoid arthritis, 7% Sjogren syndrome. PubMed. Przegl Epidemiol. 2004;58(1):227-33.
Salivary flow and its relationship to oral signs and symptoms in patients with dry eyes. Over half of the dry eye patients complained of a dry mouth. The sensation of a dry mouth and changes in oral soft tissues, dental caries, and oral Candida frequently occurred in dry eye patients. PubMed. Oral Dis. 2004 Mar;10(2):75-80.
Symptoms of Sjogren's Syndrome: Dry Mouth
Red Lips Photography by Nolan LaTourelleScleroderma Dental Involvement Scleroderma can cause many dental problems, including small mouth, dry mouth, bone reaborption, receding ligaments, and TMJ. ISN.
Implants in Patients with Sjogren’s Syndrome? I have a 62 year old female patient with Sjogren’s syndrome. Has anyone had the experience placing implants into people with Sjogren’s syndrome. OsseoNews. 05/05/08. (Also see: Dental Involvement )
Oral Manifestations of Sjögren’s Syndrome. Saliva plays an essential role in numerous functions of the mouth. Xerostomia can be caused by medications, chronic diseases like Sjögren’s syndrome, and medical treatments, such as radiation therapy and bone marrow transplant. J Dent Res 87(4):308-318, 2008.
Xerostomia - a dry subject. Xerostomia is the lessening or lack of saliva. It may be the side effect of medication, radiation treatment or the autoimmune disease Sjögren's syndrome. Smoking and alcohol make the effects of dryness much worse. While easy to diagnose, xerostomia is not easy to correct. Malden Observer. Dr. David Leader. 01/21/05.
Dentures: Evaluation of unstimulated flow rates of whole and palatal saliva in healthy patients wearing complete dentures and in patients with Sjogren's syndrome. Palatal mucous saliva may help stabilize the maxillary complete denture in patients with hyposalivation. The results suggest that neither UWS (unstimulated whole saliva) or PS (palatal saliva) flow rate are influenced by the placement of new dentures in complete denture wearers. PubMed. J Prosthet Dent. 2004 Jun;91(6):577-81. (Also see: Dental Involvement)
Taste function in Sjogren's syndrome patients with special reference to clinical tests. Our findings showed that SS patients presented taste disorders less frequently than previously reported, and we speculated that taste disorder found in SS patients were due to the salivary flow deficiency that might prevent substances from reaching the taste buds. PubMed. Auris Nasus Larynx. 2004 Jun;31(2):141-7.
Symptoms of Sjogren's Syndrome: Dry Vagina
Vaginal Lubrication in Women with Scleroderma and Sjogren's Syndrome. Sexual difficulties are often experienced by women with scleroderma, particularly those with Sjogren's syndrome. Expired link. Sexuality and Disability, Vol. 17, No. 2, ISSN 0146-1044, Kluwer Academic, Summer 1999. (Also see: Sexuality and Scleroderma and Shelley Ensz)
Symptoms of Sjogren's Syndrome: Fatigue
The Effect of Modafinil on Fatigue and Cognitive Function in Patients with Sjögren’s Syndrome (SS). Modafinil may represent a new and effective approach to treating two of the most debilitating clinical problems faced by SS patients. Thomas C. Namey. 1097/329. ACR 2007. (Also see: Fatigue )
Physical capacity in women with primary Sjogren's syndrome: a controlled study. The results indicate that women with primary SS have decreased physical capacity, which may be related to the experience of fatigue. PubMed Arthritis Rheum. 2003 Oct 15;49(5):681-8.
Symptoms of Sjogren's Syndrome: Nervous System
Autonomic nervous symptoms in primary Sjögren's syndrome (pSS). pSS patients showed subjective and objective signs of both a parasympathetic and a sympathetic dysfunction. However, autonomic dysfunction symptoms showed limited associations with objective autonomic nervous function as well as other clinical features of the disease. T. Mandl. Rheumatology Access Online. April 14,2008.
Sjogren's Syndrome and Newborn Heart Problems
Women with Sjögren's have a higher risk of having lupus and other autoimmune diseases, and of their newborns having heart problems.
Sjogren's Syndrome and Pregnancy
Sjogren's syndrome diagnosed in pregnancy: a case report. Since the presence of autoantibodies against SS-A and SS-B are reported to accompany congenital heart block, the primary goal of therapy should be preventing this untoward effect of the disease. Close monitoring during pregnancy is mandatory to detect preeclampsia, intrauterine growth retardation and preterm labor. PubMed. J Reprod Med. 2005 Jan;50(1):67-70.
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