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Scleroderma Skin Involvement: Overview

Author: Shelley Ensz. Scleroderma is highly variable. See Types of Scleroderma. Read Disclaimer
Overview
Alopecia (Hair Loss)
Calcinosis (Calcium Deposits)
Collagen, Facelifts
Digital Ulcers
Edema (Swelling)
Elbow Tip Pain
Fingernails, Nailfolds, Cuticles
Gangrene
Hypo/Hyperpigmentation
Itching (Pruritus)
Lower Extremity Ulcers
Microstomia (Small Mouth)
Neck Sign
Raynaud's
Sclerodactyly (Sclero in Hands)
Skin Fibrosis
Telangiectasia (Red Dots)
Wound Care
Xerosis (Dry Skin)

Overview of Skin Involvement in Systemic Sclerosis (SSc, scleroderma)

Skin involvement in systemic sclerosis, which includes both limited/CREST and diffuse scleroderma, can include hair loss, calcium deposits, open sores, swelling, gangrene, changes in skin color, itching, small mouth, swollen or hardened skin on fingers or elsewhere, and dry skin. When skin hardens on the fingers, it is called sclerodactyly. (Also see: What is Scleroderma?, Types of Scleroderma, and Systemic Sclerosis)
Correlates and responsiveness to change of measures of skin and musculoskeletal disease in early diffuse systemic sclerosis. Physician and patient global assessments have larger correlations with skin measures compared to musculoskeletal measures and skin variables were more responsive to change. PubMed, Arthritis Care Res (Hoboken), 2014 Apr 1. (Also see: Skeletal Involvement)

Alopecia (Hair Loss)

Alopecia (hair loss) may occur with scleroderma, if it affects the scalp. ISN.
Overview of Alopecia (Hair Loss)
Alopecia and Autoimmune Diseases
Alopecia and Scleroderma
Alopecia Treatments
Alopecia Research
Alopecia Personal Stories

Calcinosis

Calcinosis. The systemic forms of scleroderma can cause small white calcium lumps to form under the skin on fingers or other areas of the body. ISN.
Overview
Photos of Calcinosis
Diagnosis
Treatment
Stories

Collagen, Face Lifts and Scleroderma

Collagen, Face Lifts, and Scleroderma. Collagen injections should be used with caution in people who have had certain autoimmune diseases. ISN.
Overview of Collagen Injections
Collagen Injections and Autoimmune Diseases
Face Lifts and Scleroderma
Scleroderma Lips
As Cause of Autoimmune Diseases
Repair for Linear/Morphea Scleroderma

Digital (Finger) Ulcers

Digital Ulcers. Systemic scleroderma and Raynaud's can cause painful ulcers on the fingers or toes, which are known as digital ulcers. ISN.
Overview
Capillaroscopy
Treatments
-- Surgical
-- Topical
Digital Ulcer Stories
Photos
Prevention & Treatment
Raynaud's Stories
Research

Edema (Swelling)

In the initial stages, the systemic forms of scleroderma may cause edema (swelling) in the fingers.

Elbow Tip Pain

Scleroderma Elbow Tip Pains "A common area of involvement of this condition is the skin over the tips of the elbows (the olecranon area). When this skin is involved, it can lead to troublesome irritation of the tips of the elbows with tenderness noted when any pressure is applied." MedicineNet.

Fingernails, Nailfolds, and Cuticles

Fingernails, Nailfolds, and Cuticles. The systemic forms of scleroderma can cause the fingernails to become smaller, and cuticles to become hard or rough. ISN.
Overview
Cuticles: Periungual Erythema
Fingernail Abnormalities
Causes of Fingernail Symptoms and Abnormalities
Lack of Fingerprints
Manicure Safety
Nail Biting
Nailfold Capillaroscopy

Gangrene (Death of Tissue)

Gangrene and Amputations. Severe cases of scleroderma and Raynaud's may cause a total lack of blood supply to the extremities. When this happens, necrosis (death of tissue) and gangrene may set in, sometimes making it necessary to have the affected part(s) amputated. ISN.
Overview
Causes of Gangrene
Scleroderma and Smoking
Photos of Gangrene
Personal Stories
Related Pages

Hypopigmentation and Hyperpigmentation

Hypopigmentation and Hyperpigmentation. Systemic sclerosis (SSc) such as limited or diffuse scleroderma, can cause hyperpigmentation (darkening) and hypopigmention (lightening) of the skin, usually in the areas which have been affected by skin hardening. ISN.
Overview
Drug-Induced: Minocycline
Drug-Induced: Plaquenil
Salt and Pepper Appearance
Ultraviolet Light Therapy

Itching (Pruritus)

Itching may precede and accompany skin tightening in limited and diffuse systemic sclerosis (lSSc, dSSc, SSc). It is caused by the inflammation, and is a temporary phase. ISN.
Overview
Itching Emergency
Drug-Induced Skin Itching
Itching QOL and Disability
Rashes
Treatments for Itching
Xerosis (Dry Skin)

Lower Extremity Ulcers (Leg and Foot Ulcers)

Lower Extremity Ulcers in Systemic Sclerosis: Features and Response to Therapy. Lower extremity ulcers are seen in 4% of scleroderma patients and cause pain and morbidity over and above that of the scleroderma. We recommend that scleroderma patients who develop leg ulcers should undergo prothrombotic evaluation. Victoria K. Shanmugam. International Journal of Rheumatology Vol 2010, Article ID 747946. (Hindawi).
Lower extremity ulcers in systemic sclerosis: features and response to therapy. Non-digital lower extremity ulcers are a difficult to treat complication of scleroderma seen both in limited and diffuse scleroderma and also in scleroderma sine scleroderma. They contribute to the pain and disability of advanced disease. The etiology (cause) of these ulcers is unknown, but they may reflect chronic vasculopathy. PubMed, Int J Rheumatol. 2010: 747946.

Microstomia: Mouth Involvement in Systemic Scleroderma

Microstomia (Small Mouth) in a Scleroderma Patient, ISN Photo RepositoryMicrostomia. Systemic scleroderma can cause the mouth area to shrink and harden, which can impair chewing, brushing, flossing, and dental work. When the mouth becomes smaller, it is called "microstomia". ISN.
Microstomia (Small Mouth) and Scleroderma
Prevention of Microstomia
Treatments for Microstomia
Microstomia Personal Stories

Neck Sign

The Neck Sign is a distinctive pattern of yellow-brown plaque with beading and ridging. See Scleroderma Photos.

Raynaud's

Raynaud's causes blood vessel spasms, which can cause painful coldness, color changes, numbness and tingling. ISN.
What is Raynaud's?
Diagnosis
Treatments
Medications
Improving Circulation
Prevention
Rewarming Tips
Heatsock Directions
Tips from Patients
Research
Patient Support
Patient Stories

Sclerodactyly

Sclerodactyly. When fingers and/or toes become tight, stretched, wax-like, and hardened it is called sclerodactyly. ISN.
Overview
Photos
Sclerodactyly and Scleroderma
Treatments
Physical Therapy
Surgery
Sclerodactyly Personal Stories

Skin Fibrosis in Systemic Sclerosis

Skin Fibrosis. Scleroderma is named after skin fibrosis, which is one of its most common and recognizable symptoms. Skin fibrosis eventually develops in most patients. Sclero means "hard" and derma means "skin". ISN.
Overview
Diagnosis
Progression
Physical Therapy
Oral Hygiene
Treatments
d-Penicillamine
Spontaneous Remission
Myositis (Muscle Inflammation)
Research
Personal Storie

Telangiectasia

Telangiectasia may appear on the hands or face. These are tiny red dots, which are caused by blood vessels dilating near the surface of the skin. ISN.
Video Overview
Dictionary
Photos
T's in Scleroderma
Diagnosis
Treatment
Cosmetic Warnings

Corrective Cosmetics
Patient Stories: Telangiectasia
References

Wound Care

Wound Healing can be a real challenge for many scleroderma patients. Any wound that does not show improvement after a couple of days should be brought to your doctor's attention. ISN.

Xerosis (Dry Skin)

Xerosis may occur from Scleroderma causing the skin to become excessively dry. Very mild soaps and lotions (often baby products) are recommended. ISN.
What is Xerosis?
Treatments
Moisturizers
Bag Balm
Udder Cream
Baby Products
Tips from the Skin Site
The Scleroderma Bath
References
 
Go to Alopecia (Hair Loss)
 

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