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Janey Willis, ISN News GuideHello, I am Janey Willis, ISN News Manager and ISN Asst. Webmaster. David Becker, ISN Assistant News Guide researches our Autoimmune News section. Jeannie McClelland, ISN Assistant News Guide, researches Scleroderma Medical and Media News. Assistant News Guides Lisa Bulman and Judy Tarro post these stories to our Sclero Forums. Stephen Dickson prepares our RSS Newsfeed.
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July 2007
Lupus Treatments Increase Risk of Infertility in Men. Men with systemic lupus erythematosus, especially those who begin treatment with intravenous cyclophosphamide after puberty, are at risk for sperm abnormalities associated with infertility. Medpage Today. 06/28/07. (Also see: Lupus, Male Infertility, and Cytoxan )
Removing a sugar turns protective antibodies into attackers. Researcher shows that the ability of the IgG family of antibodies to efficiently trigger inflammation depends on a specific sugar molecule at the stem of the Y-shaped antibody structure. Years of prior research have confirmed that patients with autoimmune diseases have variations in the sugar patterns on their antibodies. RU Newswire. 07/04/07. (Also see: Autoimmune Diseases and Antibodies )
An audit of influenza and pneumococcal vaccination in rheumatology outpatients. Influenza and pneumococcal immunisation is suboptimal amongst patients on current immunosuppressant treatments attending rheumatology outpatient clinics. BMC Musculoskeletal Disorders 2007, 8:58. (Also see: Pulmonary Involvement: Preventative Care )
Don’t ignore that pain. Rheumatoid arthritis may start suddenly, with many joints becoming inflamed at the same time. Most often however, it starts subtly, gradually affecting the joints and may go unnoticed or ignored. The inflammation is usually symmetrical whereby if one side of the body is affected, the corresponding joint on the other side is also affected. The Star On-line. 07/01/07. (Also see: Rheumatoid Arthritis )
Alopecia - A hair loss disease. Alopecia is an autoimmune skin disease. This results in loss of hair on both the scalp and body of a person. The sufferers of Alopecia are approximately 1.7% of the population within western society with five million sufferers living in the United States alone. American Chronicle. 06/20/07. (Also see: Alopecia )
2nd Phase III CellCept Failure Sends Aspreva Shares Down. The 370-patient, 24-week, randomized, open-label study failed to prove that CellCept was superior to intravenous cyclophosphamide (IVC), a cancer drug used off-label in lupus nephritis and widely considered to be the current standard of care. BioWorld Today. 06/28/07. (Also see: Lupus and Medications )
Researchers Identify a Potential Role For Retinoic Acid In Autoimmune And Inflammatory Diseases Identified. An important finding, which could eventually lead to a new therapeutic approach for treating autoimmune and inflammatory diseases such as rheumatoid arthritis, colitis, psoriasis and others. The studies, conducted in laboratory mice, demonstrated the role of retinoic acid, a substance derived when Vitamin A is broken down in the body, in regulating inflammation. EurekAlert!. 06/1407. (Also see: Causes of Scleroderma: T Cells and Autoimmune Diseases )
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